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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1022</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Клинико-функциональные особенности бронхолегочной системы при хронической болезни почек</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and functional characteristics of bronchopulmonary system in case of chronic renal disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербань</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Scherban</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">scherbann@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ландышев</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Landyishev</surname><given-names>Yu. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State Medical University named after academician I.P. Pavlov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Амурская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Amur State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2011</year></pub-date><volume>0</volume><issue>2</issue><fpage>38</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Щербань Н.А., Ландышев Ю.С., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Щербань Н.А., Ландышев Ю.С.</copyright-holder><copyright-holder xml:lang="en">Scherban N.A., Landyishev Y.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1022">https://www.tmj-vgmu.ru/jour/article/view/1022</self-uri><abstract><p>Представлены результаты исследования клинико-функционального состояния респираторной системы у 176 пациентов на всех стадиях хронической болезни почек. Показано, что бронхолегочные осложнения начинают формироваться уже на ранних стадиях заболевания. Прогрессирующая утрата почечных функций инициирует запуск каскада патологических механизмов, приводящих к необратимым изменениям в легочной ткани. При длительной уремии происходит морфофункциональная реорганизация ткани легкого, характеризующаяся фиброзными изменениями, обусловливающими нарушение вентиляционно-перфузионных механизмов.</p></abstract><trans-abstract xml:lang="en"><p>The paper provides results of examination of clinical and functional state of the respiratory system in 176 patients at all stages of chronic renal disease development. As reported, the bronchopulmonary complications begin to form at early stages of the disease. The progressive loss of renal functions triggers a chain of pathological mechanisms that cause irreversible changes in the pulmonary tissue. The long-lasting uraemia results in morphofunctional rearrangement oflung tissue characterised by fibrous changes that determine disorders of the ventilation-perfusion mechanisms.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая болезнь почек</kwd><kwd>бронхолегочная система</kwd><kwd>функциональное исследование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic renal disease</kwd><kwd>bronchopulmonary system</kwd><kwd>functional examination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бикбов Б.Т., Кирхман В.В., Ушакова А.И. и др. Предикторы летального исхода у больных на гемодиализе // Нефрология и диализ. 2004. № 2. С. 154-163.</mixed-citation><mixed-citation xml:lang="en">Бикбов Б.Т., Кирхман В.В., Ушакова А.И. и др. Предикторы летального исхода у больных на гемодиализе // Нефрология и диализ. 2004. № 2. 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