<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1043</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Эпидемиология, патогенез и факторы риска пролапса гениталий у женщин: обзор зарубежной литературы</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiology, pathophysiologic mechanisms and risk factors for female genital prolapse: foreign literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малхасян</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Malkhasyan</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абрамян</surname><given-names>К. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Abramyan</surname><given-names>K. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State Medical Stomatological University</institution><country>Russian Federation</country></aff></aff-alternatives><aff xml:lang="ru" id="aff-2"><institution>Московский областной научно-исследовательский институт акушерства и гинекологии</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2011</year></pub-date><volume>0</volume><issue>1</issue><fpage>9</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Малхасян В.А., Абрамян К.Н., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Малхасян В.А., Абрамян К.Н.</copyright-holder><copyright-holder xml:lang="en">Malkhasyan V.A., Abramyan K.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1043">https://www.tmj-vgmu.ru/jour/article/view/1043</self-uri><abstract><p>Обзор литературы, посвященный пролапсу гениталий у женщин. Средняя частота этого заболевания среди женщин 50-80 лет варьирует в пределах 30-40 %. Риск оперативного лечения пролапса достигает своего максимума в возрасте 60-70 лет. К основным и наиболее хорошо изученным факторам риска развития пролапса гениталий можно отнести возраст, избыточный вес, количество родов естественным путем, осложненные роды, гистерэктомию, дисплазии соединительной ткани.</p></abstract><trans-abstract xml:lang="en"><p>The paper overviews literature devoted to the female genital prolapse. The average incidence rates among women aged 50 to 80 years vary in the range of 30 to 40 %. The risk of surgical treatment for the female genital prolapse reaches its maximum at the age of 60-70 years. The primary and most thoroughly studied risk factors for the genital prolapses include age, overweight, number of vaginal deliveries, complicated labours, hysterectomy, and connective tissue dysplasia.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пролапс</kwd><kwd>цистоцеле</kwd><kwd>ректоцеле</kwd><kwd>тазовое дно</kwd></kwd-group><kwd-group xml:lang="en"><kwd>prolapse</kwd><kwd>cystocele</kwd><kwd>rectocele</kwd><kwd>pelvic floor</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bradley C.S., Zimmerman M.B., Qi Y., Nygaard I.E. Natural history of pelvic organ prolapse in postmenopausal women // Obstet. Gynecol. 2007. Vol. 109, No. 4. P. 848-854.</mixed-citation><mixed-citation xml:lang="en">Bradley C.S., Zimmerman M.B., Qi Y., Nygaard I.E. Natural history of pelvic organ prolapse in postmenopausal women // Obstet. Gynecol. 2007. Vol. 109, No. 4. P. 848-854.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bump R.C., Mattiasson A., Bo K. et al. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction // Am. J. Obstet. Gynecol. 1996. Vol. 175. P. 10-17.</mixed-citation><mixed-citation xml:lang="en">Bump R.C., Mattiasson A., Bo K. et al. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction // Am. J. Obstet. Gynecol. 1996. Vol. 175. P. 10-17.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Chiaffarino F., Chatenoud L., Dindelli M. et al. Reproductive factors, family history, occupation and risk of urogenital prolapse // Eur. J. Obstet. Gynecol. Reprod. Biol. 1999. Vol. 82. P. 63-67.</mixed-citation><mixed-citation xml:lang="en">Chiaffarino F., Chatenoud L., Dindelli M. et al. Reproductive factors, family history, occupation and risk of urogenital prolapse // Eur. J. Obstet. Gynecol. Reprod. Biol. 1999. Vol. 82. P. 63-67.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Clark A.L., Gregory T., Smith V.J., Edwards R. Epidemiologic evaluation of reoperation for surgically treated pelvic organ prolapse and urinary incontinence // Am. J. Obstet. Gynecol. 2003. Vol. 189. P. 1261-1267.</mixed-citation><mixed-citation xml:lang="en">Clark A.L., Gregory T., Smith V.J., Edwards R. Epidemiologic evaluation of reoperation for surgically treated pelvic organ prolapse and urinary incontinence // Am. J. Obstet. Gynecol. 2003. Vol. 189. P. 1261-1267.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Davis G.L., Goodman M. Stress urinary incontinence in nulliparous female soldiers in Airborne Infantry training// J. Pelvic Surgery. 1996. Vol. 2. P. 68-71.</mixed-citation><mixed-citation xml:lang="en">Davis G.L., Goodman M. Stress urinary incontinence in nulliparous female soldiers in Airborne Infantry training// J. Pelvic Surgery. 1996. Vol. 2. P. 68-71.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">De Lancey J.O., Hurd W.W. Size of urogenital hiatus in the levator ani muscules in normal women and women with pelvic organ prolapse // Obstet. Gynecol. 1998. Vol. 91. P. 364-368.</mixed-citation><mixed-citation xml:lang="en">De Lancey J.O., Hurd W.W. Size of urogenital hiatus in the levator ani muscules in normal women and women with pelvic organ prolapse // Obstet. Gynecol. 1998. Vol. 91. P. 364-368.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">De Lancey J.O. The hidden epidemic of pelvic fl oor dysfunction: achievable goals for improved prevention and treatment // Am. J. Obstet. Gynecol. 2005. Vol. 192. P. 1488-1495.</mixed-citation><mixed-citation xml:lang="en">De Lancey J.O. The hidden epidemic of pelvic fl oor dysfunction: achievable goals for improved prevention and treatment // Am. J. Obstet. Gynecol. 2005. Vol. 192. P. 1488-1495.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Fritel X., Ringa V., Varnoux N. et al. Mode of delivery and fecal incontinence at midlife: a study of 2,640 women in the Gazel cohort // Obstet. Gynecol. 2007. Vol. 110, No. 1. P. 31-38.</mixed-citation><mixed-citation xml:lang="en">Fritel X., Ringa V., Varnoux N. et al. Mode of delivery and fecal incontinence at midlife: a study of 2,640 women in the Gazel cohort // Obstet. Gynecol. 2007. Vol. 110, No. 1. P. 31-38.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Handa V.L., Garrett E., Hendrix S. et al. Progression and remission of pelvic organ prolapse: a longitudinal study of menopausal women // Am. J. Obstet. Gynecol. 2004. Vol. 190. P. 27.</mixed-citation><mixed-citation xml:lang="en">Handa V.L., Garrett E., Hendrix S. et al. Progression and remission of pelvic organ prolapse: a longitudinal study of menopausal women // Am. J. Obstet. Gynecol. 2004. Vol. 190. P. 27.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hendrix S.L., Clark A., Nygaard I. et al. Pelvic organ prolapse in the Women’s Health Initiative: gravity and gravidity // Am. J. Obstet. Gynecol. 2002. Vol. 186. P. 1160-1166.</mixed-citation><mixed-citation xml:lang="en">Hendrix S.L., Clark A., Nygaard I. et al. Pelvic organ prolapse in the Women’s Health Initiative: gravity and gravidity // Am. J. Obstet. Gynecol. 2002. Vol. 186. P. 1160-1166.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Iversi E., Harvey M.A., Cardozo L. et al. Urogenital prolapse and atrophy tmenopause: a prevalence study // Int. Urogynecol. J. Pelvic Floor Dysfunct. 2001. Vol. 12. P. 107-110.</mixed-citation><mixed-citation xml:lang="en">Iversi E., Harvey M.A., Cardozo L. et al. Urogenital prolapse and atrophy tmenopause: a prevalence study // Int. Urogynecol. J. Pelvic Floor Dysfunct. 2001. Vol. 12. P. 107-110.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Karam J.A., Vazquez D.V., Lin V.K., Zimmern P.E. Elastin expression and elastic fibre width in the anterior vaginal wall of postmenopausal women with and without prolapse // BJU Int. 2007. Vol. 100, No. 2. P. 346-350.</mixed-citation><mixed-citation xml:lang="en">Karam J.A., Vazquez D.V., Lin V.K., Zimmern P.E. Elastin expression and elastic fibre width in the anterior vaginal wall of postmenopausal women with and without prolapse // BJU Int. 2007. Vol. 100, No. 2. P. 346-350.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kinn A.C. Tension-free vaginal tape evaluated using patient selfreports and urodynamic testing - a two-year follow-up // Scand. J. Urol. Nephrol. 2001. Vol. 35, No. 6. P. 484-490.</mixed-citation><mixed-citation xml:lang="en">Kinn A.C. Tension-free vaginal tape evaluated using patient selfreports and urodynamic testing - a two-year follow-up // Scand. J. Urol. Nephrol. 2001. Vol. 35, No. 6. P. 484-490.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Liu X., Zhao Y., Pawlyk B. et al. Failure of elastic fiber homeosta sis leads to pelvic floor disorders // Am. J. Pathol. 2006. Vol. 168. P. 519-528.</mixed-citation><mixed-citation xml:lang="en">Liu X., Zhao Y., Pawlyk B. et al. Failure of elastic fiber homeosta sis leads to pelvic floor disorders // Am. J. Pathol. 2006. Vol. 168. P. 519-528.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Lukacz E.S., Lawrence J.M., Contreras R. et al. Parity, mode of delivery, and pelvic floor disorders // Obstet. Gynecol. 2006. Vol. 107. P. 1253-1260.</mixed-citation><mixed-citation xml:lang="en">Lukacz E.S., Lawrence J.M., Contreras R. et al. Parity, mode of delivery, and pelvic floor disorders // Obstet. Gynecol. 2006. Vol. 107. P. 1253-1260.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Mant J., Painter R., Vessey M. Epidemiology of genital prolapse: observations from the Oxford family planning association study // BJOG. 1997. Vol. 104. P. 579-585.</mixed-citation><mixed-citation xml:lang="en">Mant J., Painter R., Vessey M. Epidemiology of genital prolapse: observations from the Oxford family planning association study // BJOG. 1997. Vol. 104. P. 579-585.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Mant J., Painter R., Vessey M. Epidemiology sexual dysfunction: definitions and classifications // J. Urol. 2000. Vol. 183. P. 888-893.</mixed-citation><mixed-citation xml:lang="en">Mant J., Painter R., Vessey M. Epidemiology sexual dysfunction: definitions and classifications // J. Urol. 2000. Vol. 183. P. 888-893.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Mentor (Nasdaq: MNTR) // Presentation at Merrill Lynch Global Medical Device Conference. 2006.</mixed-citation><mixed-citation xml:lang="en">Mentor (Nasdaq: MNTR) // Presentation at Merrill Lynch Global Medical Device Conference. 2006.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Moalli P.A., Jones I.S., Meyn L.A., Zyczynski H.M. Risk factors associated with pelvic floor disorders in women undergoing surgical repair // Obstet. Gynecol. 2003. Vol. 101. P. 869-874.</mixed-citation><mixed-citation xml:lang="en">Moalli P.A., Jones I.S., Meyn L.A., Zyczynski H.M. Risk factors associated with pelvic floor disorders in women undergoing surgical repair // Obstet. Gynecol. 2003. Vol. 101. P. 869-874.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Moalli PA, Shand SH, Zyczynski HM, Gordy SC, Meyn LA. Remodeling of vaginal connective tissue in patients with prolapse. Obstet Gynecol 2005; 106: 953-63.</mixed-citation><mixed-citation xml:lang="en">Moalli PA, Shand SH, Zyczynski HM, Gordy SC, Meyn LA. Remodeling of vaginal connective tissue in patients with prolapse. Obstet Gynecol 2005; 106: 953-63.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Norton P.A. Pelvic floor disorders: the role of fascia and ligaments // Clin. Obstet. Gynecol. 1993. Vol. 36. P. 926-936.</mixed-citation><mixed-citation xml:lang="en">Norton P.A. Pelvic floor disorders: the role of fascia and ligaments // Clin. Obstet. Gynecol. 1993. Vol. 36. P. 926-936.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Nygaard I., Bradley C., Brandt D. Women’s Health Initiative. Pelvic organ prolapse in older women: prevalence and risk factors // Obstet. Gynecol. 2004. Vol. 104. P. 489-497.</mixed-citation><mixed-citation xml:lang="en">Nygaard I., Bradley C., Brandt D. Women’s Health Initiative. Pelvic organ prolapse in older women: prevalence and risk factors // Obstet. Gynecol. 2004. Vol. 104. P. 489-497.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Olsen A.L., Smith V.J., Bergstrom J.O. et al. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence // Obstet. Gynecol. 1997. Vol. 89. P. 501-506.</mixed-citation><mixed-citation xml:lang="en">Olsen A.L., Smith V.J., Bergstrom J.O. et al. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence // Obstet. Gynecol. 1997. Vol. 89. P. 501-506.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Rinne K.M., Kirkinen P.P. What predisposes young women to genital prolapse? // Eur. J. Obstet. Gynecol. Reprod. Biol. 1999. Vol. 84. P. 23-25.</mixed-citation><mixed-citation xml:lang="en">Rinne K.M., Kirkinen P.P. What predisposes young women to genital prolapse? // Eur. J. Obstet. Gynecol. Reprod. Biol. 1999. Vol. 84. P. 23-25.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Rortveit G., Brown J.S., Thom D.H. et al. Symptomatic pelvic organ prolapse: prevalence and risk factors in a population-based, racially diverse cohort // Obstet. Gynecol. 2007. Vol. 109, No. 6. P. 1396-1403.</mixed-citation><mixed-citation xml:lang="en">Rortveit G., Brown J.S., Thom D.H. et al. Symptomatic pelvic organ prolapse: prevalence and risk factors in a population-based, racially diverse cohort // Obstet. Gynecol. 2007. Vol. 109, No. 6. P. 1396-1403.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Samuelsson E.C., Victor F.T., Tibblin G. et al. Signs of genitalprolapse in a Swedish population of women 20 to 59 years of age and possible related factors // Am. J. Obstet. Gynecol. 1999. Vol. 180. P. 299-305.</mixed-citation><mixed-citation xml:lang="en">Samuelsson E.C., Victor F.T., Tibblin G. et al. Signs of genitalprolapse in a Swedish population of women 20 to 59 years of age and possible related factors // Am. J. Obstet. Gynecol. 1999. Vol. 180. P. 299-305.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Swift S., Woodman P., O’Boyle A. et al. Pelvic Organ Support Study (POSST): the distribution, clinical definition, and epidemiologic condition of pelvic organ support defects // Am. J. Obstet. Gynecol. 2005. Vol. 192. P. 795-806.</mixed-citation><mixed-citation xml:lang="en">Swift S., Woodman P., O’Boyle A. et al. Pelvic Organ Support Study (POSST): the distribution, clinical definition, and epidemiologic condition of pelvic organ support defects // Am. J. Obstet. Gynecol. 2005. Vol. 192. P. 795-806.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Swift S.E., Pound T., Dias J.K. Case-control study of etiologic factors in the development of severe pelvic organ prolapse // Int. Urogynecol. J. Pelvic Floor Dysfunct. 2001. Vol. 12. P. 187-192.</mixed-citation><mixed-citation xml:lang="en">Swift S.E., Pound T., Dias J.K. Case-control study of etiologic factors in the development of severe pelvic organ prolapse // Int. Urogynecol. J. Pelvic Floor Dysfunct. 2001. Vol. 12. P. 187-192.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Tegerstedt G., Miedel A., Maehle-Schmidt M. et al. Obstetric risk factors for symptomatic prolapse: a population-based approach // Am. J. Obstet. Gynecol. 2006. Vol. 194, No. 1. P. 75-81.</mixed-citation><mixed-citation xml:lang="en">Tegerstedt G., Miedel A., Maehle-Schmidt M. et al. Obstetric risk factors for symptomatic prolapse: a population-based approach // Am. J. Obstet. Gynecol. 2006. Vol. 194, No. 1. P. 75-81.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Weidner A.C., Jamison M.G., Branham V. et al. Neuropathic injury to the levator ani occurs in 1 in 4 primiparous women // Am. J. Obstet. Gynecol. 2006. Vol. 195. P. 1851-1856.</mixed-citation><mixed-citation xml:lang="en">Weidner A.C., Jamison M.G., Branham V. et al. Neuropathic injury to the levator ani occurs in 1 in 4 primiparous women // Am. J. Obstet. Gynecol. 2006. Vol. 195. P. 1851-1856.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
