Objective. Summarized 10-year (2005-2015) experience in the treatment of various forms of adhesive disease of the peritoneum Methods. Conducted a retrospective and prospective, non-randomized controlled study of 279 cases of adhesive disease, using traditional surgical and laparoscopic techniques. On a material of 19,711 cases of laparoscopic surgery compared to abdominal surgery, urology and gynecology in the presence and absence of adhesions in the abdominal cavity. Results. Determined significant advantages of laparoscopic surgery: reduction in the duration of intervention, intraoperative blood loss, pain intensity, frequency of early adhesive intestinal obstruction, the term hospital treatment and the frequency of relapses. Any significant difference to the same criteria in the presence and absence of adhesions with laparoscopic procedures in the abdominal cavity is not registered. Conclusions. Surgical treatment of adhesive disease and its complications of the laparoscopic approach has significant advantages over the open surgery. Having certain manual skills and technical equipment performing total adhesiolysis is possible only using laparoscopic method. Adhesive process stage 3-4 is not a contraindication for laparoscopic correction of abdominal and retroperitoneal pathology. Moreover, in order to prevent recurrence of adhesions laparoscopic approach should be seen as a priority.