Objective. The study objective is an assessment of bone tissue condition and a prevalence of osteopenic syndrome in adolescents with chronic diseases of the gastrointestinal (GI) tract. Methods. Examined a total of 127 adolescents aged 10-15 years of dentoalveolar anomalies, including 77 people with chronic gastroduodenitis. We determines the rate of propagation of ultrasound in bone tissue, broadband ultrasound attenuation, bone strength index was calculated, assessed the presence and severity of osteopenia. To assess the risk factors of osteopenic syndrome conducted rapid surveys on the basis of an international validated tool to assess the quality of food - FFQ (Food Frequency Questionnaire). Results. Almost every teenager with dentoalveolar anomalies in conjunction with gastrointestinal diseases showed signs of calcium deficiency. Broadband ultrasound attenuation in bone tissue among boys in this group was by 2.3-2.7 lower, and most important indicators of both boys and girls were registered at 1.5-2 years later than adolescents without disease of GI tract. The incidence of osteopenic syndrome in patients with gastrointestinal diseases was by 2.4-4.3 higher. Conclusions. All teenagers with dentoalveolar anomalies in preparation for orthodontic treatment should receive advice on diet correction, and one of the combined drugs, correcting macro-and microelements homeostasis in conditions of osteopenia.