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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1203</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>СОСТОЯНИЕ СИСТОЛИЧЕСКОГО И ПУЛЬСОВОГО ДАВЛЕНИЯ В АОРТЕ ПРИ СОЧЕТАННОЙ КАРДИОРЕСПИРАТОРНОЙ ПАТОЛОГИИ</article-title><trans-title-group xml:lang="en"><trans-title>SYSTOLIC AND PULSE PRESSURE IN AORTA IN COMBINED CARDIORESPIRATORY PATHOLOGY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Невзорова</surname><given-names>В. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шекунова</surname><given-names>О. И.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голотина</surname><given-names>О. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бродская</surname><given-names>Т. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Nevzorova</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Shekunova</surname><given-names>O. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Golotina</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Brodskaya</surname><given-names>T. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Владивостокский государственный медицинский университет</institution><country>Russian Federation</country></aff><aff xml:lang="en" id="aff-2"><institution>Vladivostok State Medical University</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2009</year></pub-date><volume>0</volume><issue>4</issue><fpage>55</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Невзорова В.А., Шекунова О.И., Голотина О.В., Бродская Т.А., Nevzorova V.A., Shekunova O.I., Golotina O.V., Brodskaya T.A., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Невзорова В.А., Шекунова О.И., Голотина О.В., Бродская Т.А., Nevzorova V.A., Shekunova O.I., Golotina O.V., Brodskaya T.A.</copyright-holder><copyright-holder xml:lang="en">Невзорова В.А., Шекунова О.И., Голотина О.В., Бродская Т.А., Nevzorova V.A., Shekunova O.I., Golotina O.V., Brodskaya T.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1203">https://www.tmj-vgmu.ru/jour/article/view/1203</self-uri><abstract><p>Изучено состояние систолического и пульсового давления в аорте, его взаимосвязь с периферическим артериальным давлением и основными характеристиками жесткости аорты у 60 пациентов, страдавших хронической обструк-тивной болезнью легких (ХОБЛ) в сочетании с ишемичес-кой болезнью сердца (ИБС). Контроль - 30 здоровых лиц. Применялся метод неинвазивной артериографии. Установлено повышение аортального систолического и пульсового давления и снижение эластичности крупных сосудов в I и II стадии ХОБЛ. Подтверждена корреляция между повышением центрального и периферического артериального давления и основными характеристиками жесткости аорты. В III стадии ХОБЛ выявлено «парадоксальное» снижение центрального и периферического артериального и аортального пульсового давления. Более чувствительными показателями состояния упруго-эластических свойств крупных сосудов и миокарда оказались индекс аугментации, разность и индекс соответствия центрального и периферического систолического давления, соотношение индексов площади сердечного цикла и интервал периода изгнания левого желудочка. Указанные маркеры могут быть исполь-
зованы для оценки степени сердечно-сосудистого риска при сочетанной кардиореспираторной патологии.</p></abstract><trans-abstract xml:lang="en"><p>The paper describes systolic and pulse pressures in aorta, their relationship with peripheral arterial tension and basic characteristics of aorta rigidity, which have been observed in 60 patients suffered from chronic obstructive lung disease coupled with chronic coronary heart disease. The result of treatment is 30 healthy patients. The authors have applied a method of noninvasive arteriography and evidenced an increase in aortal systolic and pulse pressure and decrease in compliance of great blood vessels during the 1st and 2nd stages of chronic obstructive lung disease. The findings substantiate a correlation between increase of central and peripheral arterial tension and basic characteristics of aorta rigidity. The 3rd stage of chronic obstructive lung disease included "paradoxical" decrease in central and peripheral arterial and aortal pulse pressures. Among the more sensitive elastance indices of great blood vessels and myocardium are augmentation index, difference and affinity index of central and peripheral systolic pressure, relationship between indices of cardiac cycle area, and interval of left ventricle ejection period. The markers specified above may be used to evaluate the degree of cardiovascular risk in case of combined cardiorespiratory pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>центральное систолическое давление</kwd><kwd>аортальное пульсовое давление</kwd><kwd>хроническая обструктивная болезнь легких</kwd><kwd>ишемическая болезнь сердца</kwd></kwd-group><kwd-group xml:lang="en"><kwd>central systolic pressure</kwd><kwd>aortal pulse pressure</kwd><kwd>chronic obstructive lung disease</kwd><kwd>chronic coronary heart disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гельцер Б.И., Бродская Т.А. Результаты исследования центрального артериального давления у больных хронической обструктивной болезнью легких // Терапевтический архив. 2008. № 3. С. 15-19.</mixed-citation><mixed-citation xml:lang="en">Гельцер Б.И., Бродская Т.А. 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