The author has carried out epidemiologic analysis of 127 accidents involving biologic fluids taken from HIV-positive patients of medical and preventive treatment facilities in Primorsky Krai. As noted, such accidents became more frequent from 2007 to 2008. Among the participants of accidents are most often nurses (51.9%), doctors (24.4%) and medical assistants (11.8%). Most of medical workers had the HIV infection postexposure antiretroviral prophylaxis done (in 29 cases such prophylaxis was not performed due to the late visit of injured persons). Over the whole period of observations, no occupational contagion was registered. In this paper, the author also discusses measures for optimisation and 100% postexposure prophylaxis of HIV infection among the personnel of medical and preventive treatment facilities in Primorsky Krai.