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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1526</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>СОСТОЯНИЕ ИММУННЫХ И ЦИТОКИНОВЫХ МЕХАНИЗМОВ ПРИ АЛЛЕРГИЧЕСКИХ ЗАБОЛЕВАНИЯХ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>IMMUNE AND CYTOKINE MECHANISMS AT ALLERGIC DISEASES IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Просекова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Prosekova</surname><given-names>E. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Деркач</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Derkach</surname><given-names>V. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сабыныч</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sabynych</surname><given-names>V. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестовская</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestovskaya</surname><given-names>T. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>Yu. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нетесова</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Netesova</surname><given-names>S. Yu.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Владивостокский государственный медицинский университет; Дальневосточный филиал НИИ клинической иммунологии СО РАМН; Детская городская клиническая больница (г. Владивосток)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok State Medical University; Far East branch of scientific research institute of clinical immunology Siberian Branch of the Russian Academy of Medical Science; Children's city hospital (Vladivostok)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2007</year></pub-date><volume>0</volume><issue>2</issue><fpage>57</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Просекова Е.В., Деркач В.В., Сабыныч В.А., Шестовская Т.Н., Иванова Ю.В., Нетесова С.Ю., 2007</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="ru">Просекова Е.В., Деркач В.В., Сабыныч В.А., Шестовская Т.Н., Иванова Ю.В., Нетесова С.Ю.</copyright-holder><copyright-holder xml:lang="en">Prosekova E.V., Derkach V.V., Sabynych V.A., Shestovskaya T.N., Ivanova Y.V., Netesova S.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1526">https://www.tmj-vgmu.ru/jour/article/view/1526</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>The clinical and immune features of the allergic diseases (bronchial asthma, allergic rhinitis, atopic dermatitis) at children in Primorsky Krai were studied. The complex research of immune pathogenesis and cytokine structure was done. It is shown, that system changes in cytokine and immune status have been unidirectional, depend on severity of process and therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аллергические заболевания</kwd><kwd>иммунный и цитокиновый механизм</kwd><kwd>дети</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Лусс Л. В. // Consilium medicum. — 2002. — Т. 4., №4.-С. 3-13.</mixed-citation><mixed-citation xml:lang="en">Лусс Л. 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