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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1553</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Иммунологическая эффективность поликомпонентной пневмококковой вакцины у детей с заболеваниями легких</article-title><trans-title-group xml:lang="en"><trans-title>Immune efficiency of the polycomponental pneumococcal vaccine at children with respiratory diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркелова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Markelova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток;</p><p>Москва</p></bio><bio xml:lang="en"><p>Vladivostok;</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гущина</surname><given-names>Я. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Guschina</surname><given-names>Ya. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток;</p><p>Москва</p></bio><bio xml:lang="en"><p>Vladivostok;</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костинов</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostinov</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток;</p><p>Москва</p></bio><bio xml:lang="en"><p>Vladivostok;</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Владивостокский государственный медицинский университет;&#13;
Дальневосточный филиал НИИ клинической иммунологии СО РАМН;&#13;
НИИ вакцин и сывороток им. И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok state medical universit;&#13;
Far East branch of scientific research institute of clinical mmunology of the Siberian branch of the Russian Academy of Medical Science;&#13;
Scientific research vaccines institute named by I.I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2007</year></pub-date><volume>0</volume><issue>3</issue><fpage>71</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Маркелова Е.В., Гущина Я.С., Костинов М.П., 2007</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="ru">Маркелова Е.В., Гущина Я.С., Костинов М.П.</copyright-holder><copyright-holder xml:lang="en">Markelova E.V., Guschina Y.S., Kostinov M.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1553">https://www.tmj-vgmu.ru/jour/article/view/1553</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>The clinical and immunologic influence of use of the “Pneumo‑23” vaccine (France) at 42 children with bronchial asthma after pneumonias is done. Statistically authentic increase in specific antibodies (IgМ and IgG) as to the poly‑saccharide complex of the vaccine, and also to Т3, В6, 9N‑serotypes of the S.  pneumoniae is revealed, that testifies the specific post‑vaccinal immunity. Decrease in local level of the interleukin‑8 and respiratory inflammation severity is found. Safety and immune efficiency of vaccination of children with the respiratory diseases is shown.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>иммунитет</kwd><kwd>цитокины</kwd><kwd>вакцинация</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Вишнякова Л.А. // Тер. архив. – 1990. – № 11. – С. 59–62.</mixed-citation><mixed-citation xml:lang="en">Вишнякова Л.А. // Тер. архив. – 1990. – № 11. – С. 59–62.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Дрожжев М.Е., Лев Н.С., Костюченко М.В. и др. // Пульмонология. – 2002. – № 1. – С. 42–46.</mixed-citation><mixed-citation xml:lang="en">Дрожжев М.Е., Лев Н.С., Костюченко М.В. и др. // Пульмонология. – 2002. – № 1. – С. 42–46.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Клиническая аллергология и иммунология / Земсков А.М., Земсков В.М., Караулов А.В., Новикова Л.А. – Воронеж : Изд-во ВГУ, 1997.</mixed-citation><mixed-citation xml:lang="en">Клиническая аллергология и иммунология / Земсков А.М., Земсков В.М., Караулов А.В., Новикова Л.А. – Воронеж : Изд-во ВГУ, 1997.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Сидоренко Г.И., Зборовский Э.И., Левина Д.И. // Тер. архив. – 1980. – № 3. – С. 65–68.</mixed-citation><mixed-citation xml:lang="en">Сидоренко Г.И., Зборовский Э.И., Левина Д.И. // Тер. архив. – 1980. – № 3. – С. 65–68.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Суровенко Т.Н., Маркелова Е.В., Чикаловец И.В., Корявченкова И.В. Способ определения цитокинов и IgE в конденсате выдыхаемой влаги // Патент № 2222015 от 20.01.2004 г.</mixed-citation><mixed-citation xml:lang="en">Суровенко Т.Н., Маркелова Е.В., Чикаловец И.В., Корявченкова И.В. Способ определения цитокинов и IgE в конденсате выдыхаемой влаги // Патент № 2222015 от 20.01.2004 г.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Частная аллергология / под ред. Г.Б. Федосеева. – СПб. : Нормед, 2001.</mixed-citation><mixed-citation xml:lang="en">Частная аллергология / под ред. Г.Б. Федосеева. – СПб. : Нормед, 2001.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
