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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1598</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЕ ПОДХОДЫ КЛИТОЛИТИЧЕСКОЙ ТЕРАПИИ И ПРОФИЛАКТИКЕ ЖЕЛЧНО-КАМЕННОЙ БОЛЕЗНИ</article-title><trans-title-group xml:lang="en"><trans-title>MODERN APPROACHES TO LITHOLYTIC THERAPIES AND PROPHYLAXIS OF THE CHOLELITHIASIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеенко</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseenko</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Khabarovsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Наумова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Naumova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Khabarovsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агеева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ageeva</surname><given-names>E. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шацкова</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shatskova</surname><given-names>T. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Дальневосточный государственный медицинский университет (г. Хабаровск)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far Eastern State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>НИИ охраны материнства и детства (г. Хабаровск)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute of Mother and Child Protection</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Поликлиника № 3 (г. Хабаровск)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Polyclinic No. 3 (Khabarovsk)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Приморская краевая клиническая больница № 1 (г. Владивосток)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Primorsky Regional Hospital No. 1 (Vladivostok)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2006</year></pub-date><volume>0</volume><issue>1</issue><fpage>14</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексеенко С.А., Наумова Л.А., Агеева Е.А., Шацкова Т.М., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Алексеенко С.А., Наумова Л.А., Агеева Е.А., Шацкова Т.М.</copyright-holder><copyright-holder xml:lang="en">Alekseenko S.A., Naumova L.A., Ageeva E.A., Shatskova T.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1598">https://www.tmj-vgmu.ru/jour/article/view/1598</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>Cholelithiasis is one of the most widespread and expensive in the treatment of all the gastro-intestinal diseases. Standard treatment provides laparoscopic cholecystectomy. Oral litholytic therapy by bilious acids (ursodesoxycholic acid) is the alternative in patients with moderately expressed symptoms accompanying cholesterol stones. Its efficiency can be raised by the correct selection of patients. There are some potential strategies in increasing of the efficiency of prophylaxis. The efficiency of the new organizational — educational form of prophylaxis — «School of the cholelithiasis patient» is shown.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>желчно-каменная болезнь</kwd><kwd>литолитическая терапия</kwd><kwd>профилактика</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алексеенко С.А. // Урсосан — новые возможности в лечении заболеваний печени и желчевыводящих путей. - М., 2002. - С. 105-108.</mixed-citation><mixed-citation xml:lang="en">Алексеенко С.А. // Урсосан — новые возможности в лечении заболеваний печени и желчевыводящих путей. - М., 2002. - С. 105-108.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Алексеенко С.А., Абросимова Н.В., Агеева Е.А., Османова Н.Н. // Российский гастроэнтерологический журнал. - 2000. - № 2. - С. 95.</mixed-citation><mixed-citation xml:lang="en">Алексеенко С.А., Абросимова Н.В., Агеева Е.А., Османова Н.Н. // Российский гастроэнтерологический журнал. - 2000. - № 2. - С. 95.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Алексеенко С.А., Наумова Л.А., Агеева Е.А. // Экспериментальная и клиническая гастроэнтерология. - 2004. -№1.- С. 51.</mixed-citation><mixed-citation xml:lang="en">Алексеенко С.А., Наумова Л.А., Агеева Е.А. // Экспериментальная и клиническая гастроэнтерология. - 2004. -№1.- С. 51.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Abe A., Tsuchiya Y., Sugiura N. et al. // Tissue Cell. — 1997. - Vol. 29-P. 191-197.</mixed-citation><mixed-citation xml:lang="en">Abe A., Tsuchiya Y., Sugiura N. et al. // Tissue Cell. — 1997. - Vol. 29-P. 191-197.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Carey M.C. //Bile Acids — Cholestasis — Gallstones. 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