Closing of septal defects by various devices began since 1976. This technique has wide application after the device Amplatzer Septal Occluder has been invented and applied. Since 2000 the use of such devices in Russia has started, but, however, because of high cost was not accepted widely. Among 65,000 occluders implanted in the world only about 300 were implanted in Russian Federation. In December, 2005 in Primorsky Region the Amplatzer occluders have been implanted to 9 patients of 6—12 years. There were no complications in the nearest postoperative period in our series. In the long follow-up period one patient (in 2 months) had ventricle extrasystoles.