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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1639</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>ВОЗМОЖНЫЕ НАПРАВЛЕНИЯ КОРРЕКЦИИ НЕБЛАГОПРИЯТНОГО ТЕЧЕНИЯ ПСЕВДОТУБЕРКУЛЕЗА У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>POSSIBLE DIRECTIONS OF IMMUNORECONSTITUTION OF RECURRENT YERSINIA PSEUDOTUBERCULOSIS INFECTION IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бениова</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Beniova</surname><given-names>S. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Владивостокский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2006</year></pub-date><volume>0</volume><issue>4</issue><fpage>61</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бениова С.Н., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Бениова С.Н.</copyright-holder><copyright-holder xml:lang="en">Beniova S.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1639">https://www.tmj-vgmu.ru/jour/article/view/1639</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>With a view to establish the natural laws in changes of parameters of some cytokines (IL-2, IL-4, IL-8, IFN-γ) in children with Yersinia pseudotuberculosis infection in dependence of current of the disease 54 patients were examined. The obtained results revealed the hypercytokinemia with disorders of pro- and antiinflammatory pools of cytokines ratio, that proved the presence of cell-mediated immunodeficiency. The results of treatment of patients with recurrent infection by recombinant interleukin-2 (Roncoleukin) were discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>иммунитет</kwd><kwd>псевдотуберкулез</kwd><kwd>дети</kwd><kwd>ронколейкин</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Беседнова Н.Н., Сомов Г.П. // Эпидемиология и инфекционные болезни. – 2000. – № 2. – С. 52–55.</mixed-citation><mixed-citation xml:lang="en">Беседнова Н.Н., Сомов Г.П. // Эпидемиология и инфекционные болезни. – 2000. – № 2. – С. 52–55.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бениова С.Н., Гордеец А.В., Малашенкова В.Г., Седулина О.Ф. // Педиатрия. – 2001. – № 2. – С. 111–112.</mixed-citation><mixed-citation xml:lang="en">Бениова С.Н., Гордеец А.В., Малашенкова В.Г., Седулина О.Ф. // Педиатрия. – 2001. – № 2. – С. 111–112.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Гордеец А.В. 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