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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1643</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>КОРРЕКЦИЯ НАРУШЕНИЙ ЛИПИДНОГО ОБМЕНА И АНТИОКСИДАНТНОЙ АКТИВНОСТИ У БОЛЬНЫХ ПСОРИАЗОМ</article-title><trans-title-group xml:lang="en"><trans-title>CORRECTION OF LIPID METABOLIC CHANGES AND ANTIOXIDATIVE ACTIVITY AT PATIENTS WITH PSORIASIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фоменко</surname><given-names>С. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomenko</surname><given-names>S. E.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кушнерова</surname><given-names>Н. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Kushnerova</surname><given-names>N. F.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Спрыгин</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sprygin</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский океанологический институт им. В.И. Ильичева ДВО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific oceanologic institute named by V.I. Il’yichev Far-Eastern Branch of the Russian Academy of Science</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2006</year></pub-date><volume>0</volume><issue>4</issue><fpage>74</fpage><lpage>77</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фоменко С.Е., Кушнерова Н.Ф., Спрыгин В.Г., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Фоменко С.Е., Кушнерова Н.Ф., Спрыгин В.Г.</copyright-holder><copyright-holder xml:lang="en">Fomenko S.E., Kushnerova N.F., Sprygin V.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1643">https://www.tmj-vgmu.ru/jour/article/view/1643</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>Influence of biologically active additive «Kalifen» on parameters of lipid spectrum of blood and antioxidative activity at patients with psoriasis of middle severity is investigated. Under the action of medication the level of free cholesterol has decreased at the expressed tendency to stabilization of the etherificated cholesterol that is of great importance for blocking the processes of epidermis’ proliferation in the centers of injury. The natural complex from a guilder-rose positively influenced the changes in phospholipid structure of blood, restored a level of malone dialdegide and the general antioxidative activity of blood. The expediency of inclusion of «Kalifen» in complex therapy of patients with psoriasis is shown.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>липиды</kwd><kwd>антиоксидантная активность</kwd><kwd>калифен</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Айзятулов Р.Ф., Юхименко В.В. // Вестник дерматологии. – 2001. – № 1. – С. 41–43.</mixed-citation><mixed-citation xml:lang="en">Айзятулов Р.Ф., Юхименко В.В. // Вестник дерматологии. – 2001. – № 1. – С. 41–43.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Блайхер Ц., Глик Г. // Международный мед. журн. – 2000. – № 4. – С. 344–349.</mixed-citation><mixed-citation xml:lang="en">Блайхер Ц., Глик Г. // Международный мед. журн. – 2000. – № 4. – С. 344–349.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Гаскина Т.К., Курилович С.А., Горчаков В.Н. // Вопросы медицинской химии. – 1989. – Т. 35, № 4. – С. 24–28.</mixed-citation><mixed-citation xml:lang="en">Гаскина Т.К., Курилович С.А., Горчаков В.Н. // Вопросы медицинской химии. – 1989. – Т. 35, № 4. – С. 24–28.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Кешилева З.Б., Косухин А.Б., Пак А.Д., Полевая Л.Г. // Вестник дерматологии. – 1993. – № 3. – С. 45–49.</mixed-citation><mixed-citation xml:lang="en">Кешилева З.Б., Косухин А.Б., Пак А.Д., Полевая Л.Г. // Вестник дерматологии. – 1993. – № 3. – С. 45–49.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Рахматов А.Б., Муратова У.З., Файзиев К.И., Курбанова Н.К. // Украинский журнал дерматологии, венерологии и косметологии. – 2004. – № 2. – С. 16–19.</mixed-citation><mixed-citation xml:lang="en">Рахматов А.Б., Муратова У.З., Файзиев К.И., Курбанова Н.К. // Украинский журнал дерматологии, венерологии и косметологии. – 2004. – № 2. – С. 16–19.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Спрыгин В.Г., Кушнерова Н.Ф., Фоменко С.Е. и др. // Бюл. физиол. и патол. дыхания. – 2002. – Вып. 11. – С. 50–53.</mixed-citation><mixed-citation xml:lang="en">Спрыгин В.Г., Кушнерова Н.Ф., Фоменко С.Е. и др. // Бюл. физиол. и патол. дыхания. – 2002. – Вып. 11. – С. 50–53.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Спрыгин В.Г., Кушнерова Н.Ф., Рахманин Ю.А. // Гигиена и санитария. – 2003. – № 3. – С. 57–60.</mixed-citation><mixed-citation xml:lang="en">Спрыгин В.Г., Кушнерова Н.Ф., Рахманин Ю.А. // Гигиена и санитария. – 2003. – № 3. – С. 57–60.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Ухина Т.В., Кубанова А.А., Калмагамбетова Г.Ж., Сергеев П.В. // Вестник дерматологии. – 1994. – № 3. – С. 9–11.</mixed-citation><mixed-citation xml:lang="en">Ухина Т.В., Кубанова А.А., Калмагамбетова Г.Ж., Сергеев П.В. // Вестник дерматологии. – 1994. – № 3. – С. 9–11.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Фоменко С.Е., Кушнерова Н.Ф., Спрыгин В.Г., Гордейчук Т.Н. // Наркология. – 2003. – № 3. – С. 37–42.</mixed-citation><mixed-citation xml:lang="en">Фоменко С.Е., Кушнерова Н.Ф., Спрыгин В.Г., Гордейчук Т.Н. // Наркология. – 2003. – № 3. – С. 37–42.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Фортинская Е.С., Тороховская Т.И., Шарапова Г.Я. и др. // Клин. лаб. диагностика. – 1996. – № 4. – С. 38–43.</mixed-citation><mixed-citation xml:lang="en">Фортинская Е.С., Тороховская Т.И., Шарапова Г.Я. и др. // Клин. лаб. диагностика. – 1996. – № 4. – С. 38–43.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Di Carlo G., Mascolono N., Izzo A., Capasso F. // Life Sciences. – 1999. – Vol. 65, No. 4. – P. 337–353.</mixed-citation><mixed-citation xml:lang="en">Di Carlo G., Mascolono N., Izzo A., Capasso F. // Life Sciences. – 1999. – Vol. 65, No. 4. – P. 337–353.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Folch J., Less M., Sloane-Stanley G.H. // J. 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