Demographic indicators are considered to be the most important parameters characterizing the health status of the population. Methods. The factor analysis is performed and the correlation between demographic and social economic indicators of the popu lation of the Russian Far Eastern Federal District for 2010-2014 is calculated. Results. Correlation with a strong direct link is established between the number of births and housing conditions, between the number of deaths and the number of unemployed, and the number of educational organizations. The natural increase in the population was closely related to the average monthly wages, housing conditions, turnover of public catering and retail trade, as well as the volume of paid services to the population. Such a demographic criterion as the number of children who died before the age of one year did not correlate with any of the social economic indicators. The number of population was in direct connection with the number of unemployed, the number of educational organizations, and also with the production of milk. The rest of social economic indicators did not show the correlation. Conclusions. The severity of the demographic situation in the Far Eastern Federal District, even when implementing national projects, should be resolved through demographic growth or at least simple reproduction of the population and labor resources. Reducing the population can be reduced by attracting migrants, through the allocation of funds from the federal and regional budgets for the arrangement of territories, the active use of the potential of educational migration, the implementation of state policy for the development of the Russian Far East.