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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1675</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>КЛЕТОЧНЫЕ И НЕЙРОХИМИЧЕСКИЕ МЕХАНИЗМЫ КОРКОВОГО ЭПИЛЕПТОГЕНЕЗА</article-title><trans-title-group xml:lang="en"><trans-title>CELLULAR AND NEUROCHEMICAL MECHANISMS OF THE CORTEX EPILEPTOGENESIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дудина</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dudina</surname><given-names>Yu. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Владивостокский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2005</year></pub-date><volume>0</volume><issue>4</issue><fpage>11</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дудина Ю.В., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Дудина Ю.В.</copyright-holder><copyright-holder xml:lang="en">Dudina Y.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1675">https://www.tmj-vgmu.ru/jour/article/view/1675</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>The review of the literature devoted to morphology and pathogenesis of epilepsy. Despite of the big variety of ethio-pathogenetic factors of this disease and the various neural networks, pathogenetic processes have some similar moments which concern laws of formation of the centers of damage and neuron devastation. These components in hippocampus formation include nitroxide-ergic cage neurons and glutamate-ergic pyramid cells, parvalbumin- and calbindin-containing interneurons of the hippocampus and calretinin neurons of the gate of fascia serrata. In neo-cortex these are parvalbumin cage cells and cells – candelabrums, calbindin gliacytes and cells of CajalRetzius, and also astrocytes and vessels in their nearest microenvironment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпилепсия</kwd><kwd>морфология</kwd><kwd>патогенез</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дудина Ю.В. // Бюллетень экспериментальной биологии и медицины. – 2005. – Т. 139, № 3. – С. 309–312.</mixed-citation><mixed-citation xml:lang="en">Дудина Ю.В. // Бюллетень экспериментальной биологии и медицины. – 2005. – Т. 139, № 3. – С. 309–312.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Калиниченко С.Г., Дудина Ю.В., Дюйзен И.В., Мотавкин П.А. // Морфология. – 2004. – Т. 125, № 3. – С. 68–73.</mixed-citation><mixed-citation xml:lang="en">Калиниченко С.Г., Дудина Ю.В., Дюйзен И.В., Мотавкин П.А. // Морфология. – 2004. – Т. 125, № 3. – С. 68–73.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Карлов В.А. // Журнал неврологии и психиатрии им. 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