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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1740</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРГАНИЗАЦИЯ ЗДРАВООХРАНЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PUBLIC HEALTH ORGANIZATION</subject></subj-group></article-categories><title-group><article-title>ЛАБОРАТОРНЫЙ СКРИНИНГ В ОЦЕНКЕ ИММУНОЛОГИЧЕСКОГО СТАТУСА ЧАСТО БОЛЕЮЩИХ ДЕТЕЙ ДОШКОЛЬНОГО ВОЗРАСТА</article-title><trans-title-group xml:lang="en"><trans-title>LABORATORY SCREENING IN ESTIMATION OF THE IMMUNE STATUS OF THE FREQUENTLY ILL CHILDREN OF PRESCHOOL AGE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаров</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Archangelsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плаксин</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Plaksin</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Archangelsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Archangelsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северный государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Northern State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2005</year></pub-date><volume>0</volume><issue>4</issue><fpage>80</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Макаров А.И., Плаксин В.А., Макарова В.И., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Макаров А.И., Плаксин В.А., Макарова В.И.</copyright-holder><copyright-holder xml:lang="en">Makarov A.I., Plaksin V.A., Makarova V.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1740">https://www.tmj-vgmu.ru/jour/article/view/1740</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>Observed 144 children of preschool age attending preschool educational establishments, from them 89 children were the group of frequently ill. The immunologic analysis on the basis of tests of a level I and microbiological research of nasal and oral flora was done. At frequently ill children the decrease in the level of leukocytes and lymphocytes in peripheral blood, decrease in functional activity of phagocytes, increase of IgG level is revealed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>часто болеющие дети</kwd><kwd>иммунитет</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Данилов Л.А., Маккаев Х.М., Стефани Д.В. // Рос. вест. перинатол. и педиатр. – 1993. – Т. 38, № 1. – С. 27–29.</mixed-citation><mixed-citation xml:lang="en">Данилов Л.А., Маккаев Х.М., Стефани Д.В. // Рос. вест. перинатол. и педиатр. – 1993. – Т. 38, № 1. – С. 27–29.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Добродеева Л.К., Дюжикова Е.М., Щеголева Л.С. и др. // Иммунология. – 2004. – № 4. – С. 238–242.</mixed-citation><mixed-citation xml:lang="en">Добродеева Л.К., Дюжикова Е.М., Щеголева Л.С. и др. // Иммунология. – 2004. – № 4. – С. 238–242.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Иванова В.И. 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