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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1760</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>БИОМАРКЕРЫ ВОСПАЛЕНИЯ И FAS-ЗАВИСИМЫЙ АПОПТОЗ ПРИ ТЯЖЕЛОЙ ПНЕВМОНИИ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>INFLAMMATORY BIOMARKERS AND FAS-DEPENDENT APOPTOSIS AT SEVERE PNEUMONIA IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шуматова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shumatova</surname><given-names>T. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Приходченко</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Prikhodchenko</surname><given-names>N. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Владивостокский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2005</year></pub-date><volume>0</volume><issue>3</issue><fpage>41</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шуматова Т.А., Приходченко Н.Г., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Шуматова Т.А., Приходченко Н.Г.</copyright-holder><copyright-holder xml:lang="en">Shumatova T.A., Prikhodchenko N.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1760">https://www.tmj-vgmu.ru/jour/article/view/1760</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>For the evaluation of the correlation between endogen nitric oxide metabolism, change of production of a r acid glycoprotein and Fas-dependent apoptosis at severe pneumonia at 48 children the investigation of the condensate of exhaled air and blood serum was done. It is found, that the contents of inflammatory biomarkers in the condensate has been increased at all patients. Expression amplification of Fas-receptor on effector blood cells is registered. Multifactorial regression and dispersion analysis has shown that there is strong direct correlation between levels of nitric oxide metabolites and a r acid glycoprotein and CD95 in blood. The greatest influence on intensity of the Fasdependent apoptosis has the level of the a r acid glycoprotein.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>оксид азота</kwd><kwd>а^кислый гликопротеин</kwd><kwd>апоптоз</kwd><kwd>пневмония</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каганов С.Ю. //Рос. вестн. перинатологии и педиатрии. - 2003. -№3.- С. 9-16.</mixed-citation><mixed-citation xml:lang="en">Каганов С.Ю. //Рос. вестн. перинатологии и педиатрии. - 2003. -№3.- С. 9-16.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Марков Х.М. //Рос. вестн. перинатологии и педиатрии. - 2000. -№4.- С. 43-47.</mixed-citation><mixed-citation xml:lang="en">Марков Х.М. //Рос. вестн. перинатологии и педиатрии. - 2000. -№4.- С. 43-47.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Маянский А.Н., Маянский Н.А., Абадажи М.А., Заславская М.Н. //Журнал микробиологии. — 1997. — №2.-С. 88-94.</mixed-citation><mixed-citation xml:lang="en">Маянский А.Н., Маянский Н.А., Абадажи М.А., Заславская М.Н. //Журнал микробиологии. — 1997. — №2.-С. 88-94.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Пухальский А.А., Шмарин Г.Б., Лютов А.Г. и др. // Бюл. эксп. биол. и мед. — 2001. — Т. 131, № 5. — С. 564-567.</mixed-citation><mixed-citation xml:lang="en">Пухальский А.А., Шмарин Г.Б., Лютов А.Г. и др. // Бюл. эксп. биол. и мед. — 2001. — Т. 131, № 5. — С. 564-567.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Узунова А.Н., Красовская Е.В. // Педиатрия. — 2003.-№5.-С. 8-11.</mixed-citation><mixed-citation xml:lang="en">Узунова А.Н., Красовская Е.В. // Педиатрия. — 2003.-№5.-С. 8-11.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. // РМЖ. - 2004. - Т. 12, № 2. - С. 53-59.</mixed-citation><mixed-citation xml:lang="en">Чучалин А.Г. // РМЖ. - 2004. - Т. 12, № 2. - С. 53-59.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ярилин А.А. // Пат. физиол. и эксп. мед. — 1998. — № 2. - С. 38-48.</mixed-citation><mixed-citation xml:lang="en">Ярилин А.А. // Пат. физиол. и эксп. мед. — 1998. — № 2. - С. 38-48.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Юнкеров В.И., Григорьев С.Г. 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