The authors have carried out experimental investigation into the wound process course in 30 white he-rats using polypropylene implant, and showed that this implant was neutral for the organism. The wound process course, if this implant was inside, was no different from the aseptic wound process. On performing 147 surgeries using meshed implants (SurgyPRO MESH, USSC), including 79 laparoscopic hernioplasties, 17 laparoscopically assisted hernioplasties and 51 Liechtenstein hernioplasties, the authors shared their experience in identifying the indications for applying these methods of plastic surgery on hernial orifice.