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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1874</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРГАНИЗАЦИЯ ЗДРАВООХРАНЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PUBLIC HEALTH ORGANIZATION</subject></subj-group></article-categories><title-group><article-title>Опыт использования инвазивных методов пренатальной диагностики в Краевом клиническом центре охраны материнства и детства</article-title><trans-title-group xml:lang="en"><trans-title>EXPERIENCE IN APPLICATION OF INVASIVE PRENATAL DIAGNOSTICS IN REGIONAL CLINICAL CENTRE OF MATERNITY AND CHILDHOOD PROTECTION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полинтова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Polintova</surname><given-names>O. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ширин</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shirin</surname><given-names>A. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антоненко</surname><given-names>Ф. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Antonenko</surname><given-names>F. F.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Спиридонова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Spiridonova</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ульянова</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Ulyanova</surname><given-names>I. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Василенко</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilenko</surname><given-names>E. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Краевой клинический центр охраны материнства и детства (г. Владивосток); Дальневосточный филиал НЦ медицинской экологии ВСНЦ СО РАМН (г. Владивосток); Владивостокский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Centre of Maternity and Childhood Protection; Far-Eastern Branch of Research Center of Medical Ecology (Vladivostok); Vladivostok State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2004</year></pub-date><volume>0</volume><issue>4</issue><fpage>86</fpage><lpage>87</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Полинтова О.Н., Ширин А.С., Антоненко Ф.Ф., Спиридонова А.В., Ульянова И.Л., Василенко Е.М., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Полинтова О.Н., Ширин А.С., Антоненко Ф.Ф., Спиридонова А.В., Ульянова И.Л., Василенко Е.М.</copyright-holder><copyright-holder xml:lang="en">Polintova O.N., Shirin A.S., Antonenko F.F., Spiridonova A.V., Ulyanova I.L., Vasilenko E.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1874">https://www.tmj-vgmu.ru/jour/article/view/1874</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>The paper provides analysis of results of invasive prenatal diagnostics (696 cases) performed in Regional Clinical Center of Maternity and Childhood Protection (Vladivostok) over 2001-2003. Chromosomal anomalies were detected at 4.2% of cases. The most frequent pathologies were Down's syndrome and balanced translocations. Based on the findings, the authors pointed out the necessity of wider application of invasive prenatal diagnostics in the region.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хромосомные аномалии</kwd><kwd>кордоцентез</kwd><kwd>аспирация ворсин хориона</kwd><kwd>биопсия плаценты</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Медведев М.В. Пренатальная диагностика врожденных пороков развития в ранние сроки беременности. — М.: Реальное время, 2000.</mixed-citation><mixed-citation xml:lang="en">Медведев М.В. Пренатальная диагностика врожденных пороков развития в ранние сроки беременности. — М.: Реальное время, 2000.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Митьков В.В., Медведев М.В. Клиническое руководство по ультразвуковой диагностике. — М.: Видар, 1996.</mixed-citation><mixed-citation xml:lang="en">Митьков В.В., Медведев М.В. Клиническое руководство по ультразвуковой диагностике. — М.: Видар, 1996.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Климова М.И., Федотов В.П. //Пренатальная диагностика — М.: Реальное время, 1999, т. 2. — С. 112-118.</mixed-citation><mixed-citation xml:lang="en">Климова М.И., Федотов В.П. //Пренатальная диагностика — М.: Реальное время, 1999, т. 2. — С. 112-118.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
