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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1884</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>АНТИПЕРЕКИСНЫЕ ЭФФЕКТЫ ЭКСТРАКТА ИЗ ТРЕПАНГА STICHOPUS JAPONICUS</article-title><trans-title-group xml:lang="en"><trans-title>ANTIPEROXID EFFECTS OF EXTRACT FROM STICHOPUS JAPONICUS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кропотов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kropotov</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Челомин</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Chelomin</surname><given-names>V. P.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плаксен</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Plaksen</surname><given-names>N. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хильченко</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Khilchenko</surname><given-names>N. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Владивостокский государственный медицинский университет; Тихоокеанский океанологический институт им. В.И. Ильичева ДВО РАН (г. Владивосток)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok State Medical University; Pacific Oceanological Institute Far East Branch of Russian Academy of Sciences (Vladivostok)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2004</year></pub-date><volume>0</volume><issue>3</issue><fpage>18</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кропотов А.В., Челомин В.П., Плаксен Н.В., Хильченко Н.С., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Кропотов А.В., Челомин В.П., Плаксен Н.В., Хильченко Н.С.</copyright-holder><copyright-holder xml:lang="en">Kropotov A.V., Chelomin V.P., Plaksen N.V., Khilchenko N.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1884">https://www.tmj-vgmu.ru/jour/article/view/1884</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>Increased content of the lipid peroxidation products and reduced integral antiradical activity in liver tissue were found in experimental mice and rats with induced stress hypodynamia as well as in pilot rats with modeled acute carbon tetrachloride-induced hepatitis or liver fibrosis which were caused by combined administration of carbon tetrachloride and ethanol for one month. Preventive administration of an ethanol extract of stichopus to rats exerted antistress and antioxidant effects similar to the preparation of comparison silibinine.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трепанг</kwd><kwd>биологическая активность</kwd><kwd>перекисное окисление липидов</kwd><kwd>стресс</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Брехман И.И., Гоненко В.А.//Биол. науки. — 1969. — Вып. 7. - С. 51-53.</mixed-citation><mixed-citation xml:lang="en">Брехман И.И., Гоненко В.А.//Биол. науки. — 1969. — Вып. 7. - С. 51-53.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Венгеровский А.И., Саратиков А.С.// Ведомости Фарм. комитета. - 1999. - №2. - C. 9-12.</mixed-citation><mixed-citation xml:lang="en">Венгеровский А.И., Саратиков А.С.// Ведомости Фарм. комитета. - 1999. - №2. - C. 9-12.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Владимиров Ю.А., Арчаков А.И. 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