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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1898</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>СОСТОЯНИЕ ФУНКЦИИ СОСУДИСТОГО ЭНДОТЕЛИЯ ПРИ ОСТРОМ КОРОНАРНОМ СИНДРОМЕ</article-title><trans-title-group xml:lang="en"><trans-title>STATE OF VASCULAR ENDOTHELIAL FUNCTION UNDER ACUTE CORONARY SYNDROME</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Невзорова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nevzorova</surname><given-names>V. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потапова</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Potapova</surname><given-names>E. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родионова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rodionova</surname><given-names>L. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Настрадин</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nastradin</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Владивостокский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2004</year></pub-date><volume>0</volume><issue>3</issue><fpage>61</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Невзорова В.А., Потапова Е.С., Родионова Л.В., Настрадин О.В., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Невзорова В.А., Потапова Е.С., Родионова Л.В., Настрадин О.В.</copyright-holder><copyright-holder xml:lang="en">Nevzorova V.A., Potapova E.S., Rodionova L.V., Nastradin O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1898">https://www.tmj-vgmu.ru/jour/article/view/1898</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>The authors have examined 75 patients aged 37-79 suffering from acute coronary syndrome, including 22 cases of instable angina pectoris, 29 cases of large-focal myocardial infarction, and 24 cases of microinfarction. Control group was comprised of 20 healthy persons of the same age and sex. The vasomotor function of endothelium was estimated by using noninvasive ultrasonic method depending on how brachial artery responded to reactive hyperemia and nitrate intake, while the nitric oxide-producing function of endothelium was determined by nitric oxide metabolite content in blood serum. The patients suffering from the acute coronary syndrome had the nitric oxide-producing endothelial function disturbed. At the same time the state of the vasomotor and nitric oxide-producing endothelial functions did not detect any abnormalities of the parameters under examination at patients with unfavorable outcomes of the acute coronary syndrome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый коронарный синдром</kwd><kwd>сосудистый эндотелий</kwd><kwd>оксид азота</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Затейщикова А.А., Затейщиков Д.А.// Кардиология. - 1998. -№9.- С. 68-80.</mixed-citation><mixed-citation xml:lang="en">Затейщикова А.А., Затейщиков Д.А.// Кардиология. - 1998. -№9.- С. 68-80.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Иванова О.В., Балахонова Т.В., Соболева Г.Н. и др.// Кардиология. - 1997. - № 7. - С. 41-46.</mixed-citation><mixed-citation xml:lang="en">Иванова О.В., Балахонова Т.В., Соболева Г.Н. и др.// Кардиология. - 1997. - № 7. - С. 41-46.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Мотавкин П.А., Гельцер Б. 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