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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1923</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ ПЕПТИДНОГО МОРФОГЕНА ГИДРЫ И ЕГО АНАЛОГОВ НА СИСТЕМУ «ГИППОКАМП-ГИПОТАЛАМУС-ТИМУС»: ДОКАЗАТЕЛЬСТВА ИНТЕГРАЛЬНОГО ОТВЕТА</article-title><trans-title-group xml:lang="en"><trans-title>EFFECT OF PEPTIDE MORPHOGENE OF HYDRA AND ITS ANALOGUES ON "HIPPOCAMP-HYPOTHALAMUS-THYMUS" SYSTEM: EVIDENCES OF INTEGRAL RESPONSE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чимитдоржиев</surname><given-names>Ж. Ж.</given-names></name><name name-style="western" xml:lang="en"><surname>Chimitdorzhiev</surname><given-names>Zh. Zh.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Выборов</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Vyborov</surname><given-names>S. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цыганков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tzigankov</surname><given-names>V. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Дальневосточный государственный медицинский университет (г. Хабаровск)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far Eastern State Medical University (Khabarovsk)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2004</year></pub-date><volume>0</volume><issue>2</issue><fpage>50</fpage><lpage>52</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чимитдоржиев Ж.Ж., Выборов С.Г., Цыганков В.И., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Чимитдоржиев Ж.Ж., Выборов С.Г., Цыганков В.И.</copyright-holder><copyright-holder xml:lang="en">Chimitdorzhiev Z.Z., Vyborov S.G., Tzigankov V.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1923">https://www.tmj-vgmu.ru/jour/article/view/1923</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>Structural changes of elements of the "hippocamp-hypothalamus-thymus" system have been examined in vivo when introducing peptide morphogene of hydra and its three synthetic analogues. The authors have succeeded in reducing the variety of the effects under study to three ones by applying the factor analysis methods. The structure of the most powerful of them included as variables the indexes relating to both nervous and immune components.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нейроиммунная система</kwd><kwd>регуляторные пептиды</kwd><kwd>многофакторный анализ</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Абрамов В.В. Интеграция иммунной и нервной систем. — Новосибирск, 1991.</mixed-citation><mixed-citation xml:lang="en">Абрамов В.В. 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