Based on the sensitivity and specificity analysis, the authors have estimated the diagnostic value of standard methods of examination applied to the patients with mammary glands diseases associated with the galactorrhea syndrome. As is shown according to the results of the examination of 2277 patients, the diagnostic sensitivity of clinical trial has amounted to 66,4%, mammography — 0,49%, ductography 67,1%, and diagnostic specificity 93,4,99,5 and 87,1%, respectively. Allowing for the fact that none of the methods has had optimal diagnostic value while applying separately, so as to improve the quality of diagnosing it is recommended to use the whole arsenal of diagnostic facilities.