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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-1960</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>ЯДРЫШКОВЫЕ ОРГАНИЗАТОРЫ В ДИАГНОСТИКЕ РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>NUCLEOLAR ORGANIZERS IN DIAGNOSTICS OF PROSTATE GLAND CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цыганков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsigankov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Хабаровск</p></bio><bio xml:lang="en"><p>Khabarovsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельникова</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnikova</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Хабаровск</p></bio><bio xml:lang="en"><p>Khabarovsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петричко</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrichko</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Хабаровск</p></bio><bio xml:lang="en"><p>Khabarovsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Дальневосточный государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far-Eastern State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2004</year></pub-date><volume>0</volume><issue>1</issue><fpage>59</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Цыганков В.И., Мельникова Н.П., Петричко М.И., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Цыганков В.И., Мельникова Н.П., Петричко М.И.</copyright-holder><copyright-holder xml:lang="en">Tsigankov V.I., Melnikova N.P., Petrichko M.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/1960">https://www.tmj-vgmu.ru/jour/article/view/1960</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>In the present paper the authors, based on the computer-based morphometry of the nucleolar zones, make division of nucleolar-nuclear indices of prostate gland biopsy material epithelium of 183 patients having benign and malignant diseases into 6 groups, which are characterized by certain morphometric histotypes being correlated with concrete clinicopathologic forms. Visual analysis of quantity of nucleolar organizers has indicated their regular increase while passing to higher histotype. The findings testify the high self-descriptiveness of the computer-based morphometry of nucleolar-nuclear apparatus in differential diagnostics of the prostate gland diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак</kwd><kwd>предстательная железа</kwd><kwd>компьютерная морфометрия</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Автандилов Г.Г.//Архив патологии. — 1993. — №2. — С. 4-7.</mixed-citation><mixed-citation xml:lang="en">Автандилов Г.Г.//Архив патологии. — 1993. — №2. — С. 4-7.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Мамаев Н.Н., Бебия Н.М., Мамаева С.Е. и др.//Бюл. эксперим. биологии и медицины. — 1985. — № 4. — С. 477-478.</mixed-citation><mixed-citation xml:lang="en">Мамаев Н.Н., Бебия Н.М., Мамаева С.Е. и др.//Бюл. эксперим. биологии и медицины. — 1985. — № 4. — С. 477-478.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Применение персональных компьютеров в морфологи- ческой диагностике методом многомерной статис- тики// Алиякпаров М.А., Акимжанов Р.Х., Жукоц- кий А.В. и др. — Караганда, 1991.</mixed-citation><mixed-citation xml:lang="en">Применение персональных компьютеров в морфологи- ческой диагностике методом многомерной статис- тики// Алиякпаров М.А., Акимжанов Р.Х., Жукоц- кий А.В. и др. — Караганда, 1991.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Цыганков В.И., Мельникова Н.П., Петричко М.И. и др.// Дальневосточный медицинский журнал. — 2001.-№3.-С. 14-17.</mixed-citation><mixed-citation xml:lang="en">Цыганков В.И., Мельникова Н.П., Петричко М.И. и др.// Дальневосточный медицинский журнал. — 2001.-№3.-С. 14-17.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Contractor H., Ruschoff J., Hanish T. et al.// J. 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