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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-2061</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>ЦЕНТРАЛЬНЫЕ И ПЕРИФЕРИЧЕСКИЕ НИТРОКСИДЕРГИЧЕСКИЕ МЕХАНИЗМЫ В РЕАЛИЗАЦИИ ЭФФЕКТОВ ФАРМАКОЛОГИЧЕСКИХ ПРЕПАРАТОВ</article-title><trans-title-group xml:lang="en"><trans-title>CENTRAL AND PERIPHERAL NITROXYDERGICAL MECHANISMS IN COURSE OF REALIZATION OF EFFECTS OF PHARMACOLOGICAL PREPARATIONS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елисеева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Eliseeva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городская клиническая больница № 2;&#13;
Владивостокский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Municipal Clinical Hospital No. 2;&#13;
Vladivostok State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2003</year></pub-date><volume>0</volume><issue>3</issue><fpage>18</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Елисеева Е.В., 2003</copyright-statement><copyright-year>2003</copyright-year><copyright-holder xml:lang="ru">Елисеева Е.В.</copyright-holder><copyright-holder xml:lang="en">Eliseeva E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/2061">https://www.tmj-vgmu.ru/jour/article/view/2061</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>In this article the author brings up for discussion the findings of original experimental and clinical investigations that witness to nitric oxide participation in course of realization of effects of pharmacological preparations. By using of the model of multilevel regulation of respiratory function, the physician demonstrates the participation of central and peripheral nitroxydergical mechanisms of action of adrenoreactive and cholinoreactive medications by means of different isoforms of nitroxyde synthase.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>оксид азота</kwd><kwd>нитрооксидсинтаза</kwd><kwd>фармакотерапия</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Елисеева Е.В. Нитрооксидергическая регуляция легких. – Владивосток, 2001.</mixed-citation><mixed-citation xml:lang="en">Елисеева Е.В. 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