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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2021-1-24-27</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-2156</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group></article-categories><title-group><article-title>Костно-суставной туберкулез у детей: что изменилось в концепции и стратегии частной проблемы современной фтизиатрии?</article-title><trans-title-group xml:lang="en"><trans-title>Tuberculosis of bones and joints among children: What has changed in the concept and strategy of a particular modern phthisiatry issue?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1342-3278</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мушкин</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mushkin</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мушкин Александр Юрьевич – доктор медицинских наук, профессор, руководитель центра патрологии позвоночника, руководитель клиники детской хирургии и ортопедии, главный научный сотрудник.</p><p>191036, Санкт-Петербург, Лиговский пр-т, 2-4</p></bio><bio xml:lang="en"><p>Aleksandr Yu. Mushkin, MD, PhD, professor, chief researcher.</p><p>2-4 Ligovsky Ave., Saint Petersburg, 191036</p></bio><email xlink:type="simple">aymushkin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2358-5529</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петухова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petukhova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петухова Вероника Витальевна – аспирант.</p><p>191036, Санкт-Петербург, Лиговский пр-т, 2-4</p></bio><bio xml:lang="en"><p>Veronika V. Petukhova, MD, postgraduate student.</p><p>2-4 Ligovsky Ave., Saint Petersburg, 191036</p></bio><email xlink:type="simple">aymushkin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии; Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg Research Institute of Phthisiopulmonology; Pavlov First Saint Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg Research Institute of Phthisiopulmonology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>21</day><month>03</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>24</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мушкин А.Ю., Петухова В.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Мушкин А.Ю., Петухова В.В.</copyright-holder><copyright-holder xml:lang="en">Mushkin A.Y., Petukhova V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/2156">https://www.tmj-vgmu.ru/jour/article/view/2156</self-uri><abstract><p>Лекция, посвященная современным подходам к диагностике и лечению костно-суставного туберкулеза у детей. Рассмотрены вопросы этиологической доказательности диагноза «туберкулез костей и суставов» и особенности костных осложнений противотуберкулезной вакцинации. Подчеркивается, что в соответствии с рекомендациями ВОЗ, диагноз туберкулеза может рассматриваться как установленный, но недоказанный, и как установленный и верифицированный. При этом верифицированным считается диагноз, имеющий бактериологическое подтверждение. Специфический характер костного поражения может быть установлен только на материале из очага поражения. Хирургическое лечение костно-суставного туберкулеза у детей должно быть максимально приближено к моменту установления диагноза, а послеоперационная химиотерапия - проводиться с учетом верификации патогенного штамма и его лекарственной чувствительности. Таким образом, костно-суставной туберкулез у детей требует двухуровневого доказательства диагноза, его этапной верификации и синдромно-нозологического терапевтического сопровождения.</p></abstract><trans-abstract xml:lang="en"><p>The lecture is devoted to the current approaches to diagnosing and treating tuberculosis of bones and joints among children. Issues of the evidentiary standards of the diagnosis "tuberculosis of bones and joints" and peculiarities of the skeletal-related event of anti-tuberculosis immunization are discussed. It is highlighted that according to WHO's recommendations tuberculosis can be considered as diagnosed, but not proved and also as diagnosed and verified. Diagnosis is considered verified when it has bacteriological proof. The specific character of the bone disorder can be diagnosed only by testing material from lesion. The surgical treatment of the tuberculosis of joints and bones among children should be as close as possible to the moment of diagnosing. After surgery chemotherapy is conducted taking into account verification of the pathogenic strains and its drug sensitivity. Thus tuberculosis of joints and bones among children requires two-level proof of the diagnosis, its stage-by-stage verification and syndrome-nosologic support.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>костно-суставной туберкулез</kwd><kwd>дети</kwd><kwd>хронический остеомиелит</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tuberculosis of bones and joints</kwd><kwd>children</kwd><kwd>chronic osteitis</kwd><kwd>diagnostics</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hogan JI, Hurtado RM, Nelson SB. Mycobacterial musculoskeletal infections. Infect Dis Clin North Am. 2017;31(2):369-82.</mixed-citation><mixed-citation xml:lang="en">Hogan JI, Hurtado RM, Nelson SB. 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