pmjТихоокеанский медицинский журналPacific Medical Journal1609-1175TGMU10.34215/1609-1175-2021-4-26-33pmj-2263Research ArticleОБЗОРЫREVIEWSМеханизмы и регуляторные факторы неоваскуляризации эндометрияMechanisms and regulatory factors of endometrial neovascularizationhttps://orcid.org/0000-0002-1107-4561ЧертокВ. М.ChertokV. M.

Черток Виктор Михайлович, д.м.н., профессор, зав. кафедрой анатомии человека

Тел. моб. 89502858347

690002, г. Владивосток, пр-т.  Острякова, 2

Victor M. Chertok – Doctor of Medical Science, Professor, Head Department of Human Anatomy

690002, Vladivostok, Russia, 2 Ostryakova Av.

chertokv@mail.ruКоцюбаА. Е.KotsyubaA. E.

Коцюба Александр Евгеньевич  – д.м.н., доцент, профессор кафедры анатомии человека

т. +7 (950)281-36-13

690002, г. Владивосток, ул. Острякова, д. 2

Alexander E. Kotsyuba – Doctor of Medical Science, Associate Professor, Professor Anatomy Depatment

690002, Vladivostok, Russia, 2 Ostryakova Av. 

akotc@mail.ruХрамоваИ. А.KhramovaI. A.

Храмова Ирина Афанасьевна – д.м.н., профессор, профессор кафедры акушерства и гинекологии

т. +7(914)731-24-33

690002, г. Владивосток, ул. Острякова, д. 2

Irina A. Khramova – Doctor of Medical Science, Professor, Professor Department of Obstetrics and Gynecology

690002, Vladivostok, Russia, 2 Ostryakova Av.

khramova@mail.ruТихоокеанский государственный медицинский университетРоссияPacific State Medical UniversityRussian Federation202106012022042633Copyright © Черток В.М., Коцюба А.Е., Храмова И.А., 20222022Черток В.М., Коцюба А.Е., Храмова И.А.Chertok V.M., Kotsyuba A.E., Khramova I.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tmj-vgmu.ru/jour/article/view/2263

Клеточно-молекулярные механизмы и факторы, регулирующие новообразование кровеносных сосудов матки, относятся также к ключевым звеньям, обеспечивающим процессы репродукции. В ходе ангиогенеза эндотелий экспрессирует ряд рецепторов факторов роста и лигандов, которые контролируют основные этапы формирования клеточного состава стенки сосудов, что, в свою очередь, способствует пролиферации и репарации эндометрия на протяжении менструального цикла, обеспечивают его подготовку к имплантации и плацентации.

Cellular-molecular mechanisms and factors, regulating uterus vascularization are also a focal point ensuring reproduction processes. In the process of angiogenesis endothelium expresses a number of receptors of growth factors and ligands which control main stages of the cellular makeup during vascular walls formation process. It in turn supports proliferation and reparation of the endometrium during menstrual cycle and prepares for the implantation and placentation.

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The authors declare that there are no conflicts of interest present.