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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2021-4-41-45</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-2265</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Клинико–лабораторные особенности течения инфекции мочевыводящих путей у детей первых трех лет жизни на современном этапе</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and laboratory features of the course of the urinary tract infection among children in the first three years of life at the current stage</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6926-3341</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ни</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nее</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ни Антонина, доктор медицинских наук, профессор Института педиатрии</p><p>тел. 8(423)242–07–16</p><p>690002, г. Владивосток, проспект Острякова, 2</p></bio><bio xml:lang="en"><p>Antonina Nee, Doctor of Medical Sciences, Professor of Institute of Pediatrics</p><p>Phone: 8(423)242–07–16</p><p>2 prospect Ostryakova, Vladivostok, 690002, Russia</p></bio><email xlink:type="simple">neeant56@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4465-3471</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергеева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeeva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергеева Елена Васильевна – ассистент Института педиатрии</p><p>тел. 89143271168</p><p>690002, г. Владивосток, проспект Острякова, 2</p></bio><bio xml:lang="en"><p>Elena V. Sergeeva – assistant of the Institute of Pediatrics</p><p>Phone: 8(423)242–07–16</p><p>2 prospect Ostryakova, Vladivostok, 690002, Russia</p></bio><email xlink:type="simple">sergeeva.elenav@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2413-4022</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быкова</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Bykova</surname><given-names>O. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Быкова Ольга Геннадьевна – кандидат медицинских наук, доцент института педиатрии</p><p>тел. 8(423)242–07–16</p><p>690002, г. Владивосток, проспект Острякова, 2</p></bio><bio xml:lang="en"><p>Оlga G. Bykova – Cand. of Sci. (Med.), Associate Professor, Institute of Pediatrics</p><p>Phone: 8(423)242–07–16</p><p>2 prospect Ostryakova, Vladivostok, 690002, Russiа</p></bio><email xlink:type="simple">lis822007@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семешина</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Semeshina</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семешина Ольга Владимировна – кандидат медицинских наук, заведующая отделением нефрологии; доцент института педиатрии</p><p>тел. 8(423)242–07–16</p><p>690002, г. Владивосток, проспект Острякова, 2</p><p> </p></bio><bio xml:lang="en"><p>Olga V. Semeshina – Cand. of Sci. (Med.), Head of the Department of Nephrology; Associate Professor, Institute of Pediatrics</p><p>Phone: 8(423)242–07–16</p><p>2 prospect Ostryakova, Vladivostok, 690002, Russiа</p></bio><email xlink:type="simple">sova31@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет; Краевая детская клиническая больница № 1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University; Regional Children’s Clinical Hospital № 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>06</day><month>01</month><year>2022</year></pub-date><volume>0</volume><issue>4</issue><fpage>41</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ни А., Сергеева Е.В., Быкова О.Г., Семешина О.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ни А., Сергеева Е.В., Быкова О.Г., Семешина О.В.</copyright-holder><copyright-holder xml:lang="en">Nее A., Sergeeva E.V., Bykova O.G., Semeshina O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/2265">https://www.tmj-vgmu.ru/jour/article/view/2265</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить основные клинические и лабораторные особенности течения ИМВП у детей первых трех лет жизни.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Дизайн исследования – проспективное контролируемое клиническое исследование. В первую группу вошли 102 (60,71±3,77 %) ребенка с инфекцией мочевыводящих путей без сопутствующих аномалий развития органов мочевой системы, а во вторую – 66 (39,29±3,77%) детей с инфекцией мочевыводящих путей на фоне врожденных пороков почек.</p></sec><sec><title>Результаты</title><p>Результаты. Сравнительная оценка результатов комплексного обследования обеих групп показала, что для детей грудного и раннего возраста в клинике инфекции мочевыводящих путей характерен интоксикационный, болевой и дизурический синдромы. Наличие сопутствующих врожденных пороков развития почек и мочевыводящих путей определяет латентное течение заболевания у каждого второго ребенка (59,09 %) и способствует раннему развитию ренальной инфекции (первые 6 месяцев жизни).</p></sec><sec><title>Заключение</title><p>Заключение. Необходим поиск диагностических маркеров и предикторов инфекции мочевыводящих путей у детей первых лет жизни, особенно при наличии аномалий органов мочевой системы.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: To study main clinical and laboratory peculiarities of the course of urinary tract disease among children aged from newborns to 3 years old.</p></sec><sec><title>Methods</title><p>Methods: Research design is a prospective controlled clinical research. 102 (60.71±3.77 %) children having urinary tract infection without accompanying abnormalities of the urinary system development were included in the first group. 66 (39.29±3.77 %) children having infection of the urinary tract amid congenital kidney defect.</p></sec><sec><title>Results</title><p>Results: Comparative evaluation of the results of complex examination of both groups showed that urinary tract infection is characterized by intoxication, pain and dysuric syndroms. The presence of accompanying kidneys and urinary tract abnormality development defined the latent course of the disease in every second child (59.09%) and supports the early development of renal infection (during first six months after birth).</p></sec><sec><title>Conclusions</title><p>Conclusions: It’s necessary to conduct the search of diagnostics markers and predictors of the infection of the urinary tract among children of the first years of life, especially if there is an abnormality of the organs of urinary system.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инфекция мочевыводящих путей</kwd><kwd>дети раннего возраста</kwd><kwd>врожденные пороки развития почек</kwd><kwd>диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>urinary tract infection</kwd><kwd>children of the early age</kwd><kwd>congenital abnormality of the kidneys development</kwd><kwd>diagnostics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">‘Hoen LA, Bogaert G, Radmayr C, Dogan HS, Nijman RJM, Quaedackers J, Rawashdeh YF, Silay MS, Tekgul S, Bhatt NR, Stein R. 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