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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2022-1-56-64</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-2300</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Кардиоваскулярная составляющая постковидного синдрома</article-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular component of post-COVID-19-syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4287-1221</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вахненко</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vakhnenko</surname><given-names>Y. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вахненко Юлия Викторовна - кандидат медицинских наук, ассистент, кафедра госпитальной терапии с курсом фармакологии.</p><p>675000, Амурская область, Благовещенск, ул. Горького, 97; тел. +7(924)677-00-08</p></bio><bio xml:lang="en"><p>Yulia V. Vakhnenko - M.D., Assistant, Department of Hospital Therapy with a Course of Pharmacology.</p><p>675000, Blagoveshchensk, Amur Region, 97 Gorky St.; тел. +7(924)677-00-08</p></bio><email xlink:type="simple">gen-45@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Доровских</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Dorovskikh</surname><given-names>I. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доровских Ирина Евгеньевна - кандидат медицинских наук, зав. диагностическим отделением.</p><p>675000, Амурская область, Благовещенск, ул. Горького, 97; тел. +7(924)671-59-58</p></bio><bio xml:lang="en"><p>Irina E. Dorovskikh - M.D., Head of the Functional Diagnostic Department of the Clinic of Cardiac Surgery.</p><p>675000, Blagoveshchensk, Amur region, 97 Gorky str.; тел. +7(924)671-59-58</p></bio><email xlink:type="simple">irina_dorovsk@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0014-9118</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Домке</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Domke</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Домке Алексей Павлович - врач-сосудистый хирург Клиники кардиохирургии.</p><p>675000, Амурская область, г. Благовещенск, ул. Горького, 97; тел. +7(909) 814-20-29</p></bio><bio xml:lang="en"><p>Alexey P. Domke - M.D., M.D., vascular surgeon at the Cardiosurgery Clinic.</p><p>97 Gorky str., Blagoveshchensk, Amur region, 675000; тел. +7(909) 814-20-29</p></bio><email xlink:type="simple">aldomke@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Амурская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Amur State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>26</day><month>03</month><year>2022</year></pub-date><volume>0</volume><issue>1</issue><fpage>56</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Вахненко Ю.В., Доровских И.Е., Домке А.П., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Вахненко Ю.В., Доровских И.Е., Домке А.П.</copyright-holder><copyright-holder xml:lang="en">Vakhnenko Y.V., Dorovskikh I.E., Domke A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/2300">https://www.tmj-vgmu.ru/jour/article/view/2300</self-uri><abstract><p>Наблюдение за больными, перенесшими острый COVID-19, показывает, что у многих из них продолжительное время сохраняются различные симптомы, которые нередко значительно ухудшают качество жизни и объединены понятием «постковидный синдром». Изучение этого феномена активно продолжается, но уже известны его типы и проявления, создаются регистры больных, ведется мониторинг их состояния, а сам постковидный синдром внесен в Международную классификацию болезней. В обзоре рассматриваются предикторы, механизмы развития и основные признаки Long-Covid, системность поражения внутренних органов, которая объясняется, в том числе, повреждающим действием вируса на разные ткани, эндотелиальной дисфункцией, микротромбозами. Особое внимание уделено причинам и вариантам поражения кардиоваскулярной системы. Обозначены особенности функционирования мировой системы здравоохранения в период волн пандемии, повлиявшие на сердечно-сосудистую заболеваемость и смертность. Подчеркнуто, что постковидному синдрому подвержены как лица, перенесшие острую COVID в тяжелой форме, так и бессимптомные и малосимптомные пациенты. Все они в равной мере нуждаются во внимании медиков, обеспечить которое в условиях пандемии помогают электронные средства связи.</p></abstract><trans-abstract xml:lang="en"><p>Observation of patients suffering from acute COVID-19 shows that many of them have a long persistence of various symptoms, which often significantly worsen the quality of life and are combined with the concept of "postvoid syndrome". The study of this phenomenon is actively continuing, but its types and manifestations are already known, registers of patients are created, their condition is monitored, and postcovid syndrome is included in the International Classification of Diseases. The review covers predictors, mechanisms of development and main signs of Long-Covid, systemic affection of internal organs, which is explained, among other things, by damaging effect of the virus on different tissues, endothelial dysfunction and micro thrombosis. Particular attention is paid to the causes and types of cardiovascular system disorders. The features of functioning of the world health care system during the pandemic waves which influenced the cardiovascular morbidity and mortality are outlined. It is emphasized that postvascular syndrome is susceptible both to persons who had acute form of COVID and to asymptomatic patients. They equally require medical attention. Electronic means of communication help to provide such care during pandemic period.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>постковидный синдром</kwd><kwd>предикторы</kwd><kwd>патогенез</kwd><kwd>типы и симптомы</kwd><kwd>телемедицина</kwd><kwd>реабилитация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>postvoid syndrome</kwd><kwd>predictors</kwd><kwd>pathogenesis</kwd><kwd>types and symptoms</kwd><kwd>telemedicine</kwd><kwd>rehabilitation</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">авторы заявляют о финансировании проведенного исследования из собственных средств</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hendren N.S., Drazner M.H., Bozkurt B., Cooper L.T. Description and Proposed Management of the Acute COVID-19 Cardiovascular Syndrome. 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