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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2023-1-81-85</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-2477</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Микрофлора ран и резистентность к антибиотикам у пострадавших с термической травмой</article-title><trans-title-group xml:lang="en"><trans-title>Wound microflora and antibiotic resistance in burn patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2087-543X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потапов</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Potapov</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Потапов Александр Филиппович – д-р мед. наук, доцент, профессор кафедры анестезиологии, реаниматологии и интенсивной терапии с курсом скорой медицинской помощи факультета последипломного обучения врачей</p><p>677000, Республика Саха (Якутия), г. Якутск, ул. Ойунского, 27</p></bio><bio xml:lang="en"><p>Alexander F. Potapov, Dr. Sci. (Med.), Associate Professor, Professor of Department of Anesthesiology, Resuscitation and Intensive Care with a course of emergency medicine of the Faculty of Postgraduate Training of Doctors </p><p>27 Oyunsky str., Yakutsk, 677000, Republic of Sakha (Yakutia)</p></bio><email xlink:type="simple">potapov-paf@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамаева</surname><given-names>С. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamaeva</surname><given-names>S. H.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якутск</p></bio><bio xml:lang="en"><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якутск</p></bio><bio xml:lang="en"><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якутск</p></bio><bio xml:lang="en"><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинский институт Северо-Восточного федерального университета имени М.К. Аммосова; Республиканская больница № 2 – Центр экстренной медицинской помощи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Institute of the North-Eastern Federal University named after M.K. Ammosov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Республиканская больница № 2 – Центр экстренной медицинской помощи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Hospital № 2 – Emergency Medical Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Медицинский институт Северо-Восточного федерального университета имени М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Institute of the North-Eastern Federal University named after M.K. Ammosov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>14</day><month>04</month><year>2023</year></pub-date><volume>0</volume><issue>1</issue><fpage>81</fpage><lpage>85</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Потапов А.Ф., Шамаева С.Х., Иванова А.А., Семенова С.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Потапов А.Ф., Шамаева С.Х., Иванова А.А., Семенова С.В.</copyright-holder><copyright-holder xml:lang="en">Potapov A.F., Shamaeva S.H., Ivanova A.A., Semenova S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/2477">https://www.tmj-vgmu.ru/jour/article/view/2477</self-uri><abstract><sec><title>Цель</title><p>Цель: Изучение этиологической структуры микрофлоры ран и ее чувствительности к антибактериальным препаратам у пострадавших с термическими ожогами в специализированных отделениях для пациентов с термической травмой.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Анализированы результаты микробиологических исследований 2354 проб отделяемого раневой поверхности 1581 пострадавшего с тяжелыми термическими ожогами, лечившихся в ожоговом отделении и в отделении анестезиологии, реанимации и интенсивной терапии Центра экстренной медицинской помощи Республики Саха (Якутия) в период с 2016 по 2020 г. Обработка данных и анализ антибиотикорезистентности выполнены на онлайн-платформе AMRcloud (версия: Beta, 05.07.2022).</p></sec><sec><title>Результаты</title><p>Результаты. Выявлено, что в ожоговых ранах среди выделенных возбудителей доля Staphylococcus aureus составила 26,1%, Enterococcus faecalis – 24,5%, Pseudomonas aeruginosa – 11,9%, Klebsiella pneumonia – 9,4%, Acinetobacter baumannii – 7,9% и Escherichia coli – 6,0%. Установлена чувствительность выделенных штаммов микроорганизмов к карбапенемам и высокая резистентность к цефалоспоринам и фторхинолонам.</p></sec><sec><title>Заключение</title><p>Заключение. Микробные штаммы, выявленные у пациентов с термическими ожогами, свидетельствует об инфицировании ран представителями внутрибольничной микрофлоры и их высокой резистентности к часто используемым антибиотикам.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To explore the etiological structure of wound microflora and its antimicrobial susceptibility in burn patients treated in hospital burn departments.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The authors analyzed the microbiology testing results of 2354 wound exudates in samples of 1581 patients with severe burns who underwent treatment in the Burn Unit and Department of Anesthesiology, Resuscitation and Intensive Care of the Center for Emergency Medical Care of the Republic of Sakha (Yakutia) in the period from 2016 to 2020. Data processing and antibiotic resistance analysis were performed via AMRcloud online platform (Beta version, 05.07.2022).</p></sec><sec><title>Results</title><p>Results. Of the pathogens isolated in the burn wounds, Staphylococcus aureus accounted for 26.1%, Enterococcus faecalis – 24.5%, Pseudomonas aeruginosa – 11.9%, Klebsiella pneumonia – 9.4%, Acinetobacter baumannii – 7.9% and Escherichia coli – 6.0%. The susceptibility of isolated microbial strains to carbapenems and high resistance to cephalosporins and fluoroquinolones were established.</p></sec><sec><title>Conclusion</title><p>Conclusion. Microbial strains detected in burn patients indicate infection of wounds with representatives of nosocomial flora and their high resistance to commonly used antibiotics.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>термическая травма</kwd><kwd>ожоговая рана</kwd><kwd>микрофлора ран</kwd><kwd>внутрибольничная инфекция</kwd><kwd>антибиотикорезистентность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thermal injury</kwd><kwd>burn wound</kwd><kwd>microflora of wounds</kwd><kwd>nosocomial infection</kwd><kwd>antibiotic resistance</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">авторы заявляют о финансировании работы из собственных средств.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. Burns, 2018. 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