pmjТихоокеанский медицинский журналPacific Medical Journal1609-1175TGMU10.34215/1609-1175-2023-2-20-24pmj-2512Research ArticleОБЗОРЫREVIEWSБеталаины в практической медицинеBetalains in practical medicinehttps://orcid.org/0000-0002-6206-200XКолдаевВ. М.KoldaevV. M.

Колдаев Владимир Михайлович – доктор биологических наук, профессор, ведущий научный сотрудник лаборатории лекарственных растений ФНЦ биоразнообразия наземной биоты Восточной Азии Дальневосточного отделения Российской академии наук

690022, Владивосток, проспект 100-летия Владивостока, 159

Vladimir M. Koldaev - Dr. Sci. (Biol.), Prof., Leading Researcher, Laboratory of Medicinal Plants

159 Stoletiya Vladivistoka Prospect, Vladivostok, 690022

kolvm42@rambler.ruКропотовА. В.KropotovA. V.

Владивосток

Vladivostok

ЛиО. Н.LiO. N.

Владивосток

Vladivostok

Федеральный научный центр биоразнообразия наземной биоты Восточной Азии Дальневосточного отделения Российской академии наукРоссияFederal Scientific Center of the East Asia Terrestrial Biodiversity, Far Eastern Branch of the Russian Academy of SciencesRussian FederationТихоокенский государственный медицинский университетРоссияPacific State Medical UniversityRussian Federation202314062023022024Copyright © Колдаев В.М., Кропотов А.В., Ли О.Н., 20232023Колдаев В.М., Кропотов А.В., Ли О.Н.Koldaev V.M., Kropotov A.V., Li O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tmj-vgmu.ru/jour/article/view/2512

Беталаины – растительные пигменты, синтезируются в клетках гвоздикоцветных (красная свекла, опунция и др.), участвуют в инактивации активных форм кислорода и свободных радикалов. В обзоре суммированы данные по физико-химическим и фармакологическим свойствам беталаинов. Беталаины устраняют последствия окислительного стресса, эффективны в коррекции метаболических нарушений при сахарном диабете и абдоминальном ожирении, снижают риск сердечно-сосудистых заболеваний. Обогащенная беталаинами диета оказывает широкий спектр противоракового действия. Беталаины защищают от окислительных повреждений дофаминэргические нейроны головного мозга и снижают выраженность нейродегенеративных расстройств при болезни Альцгеймера и Паркинсона. Однако беталаины малоустойчивы и подвергаются деградации при переработке и хранении растительного сырья. Подчеркивается актуальность разработки новых, не повреждающих технологий беталаинсодержащих фитопрепаратов.

Betalains are plant pigments synthesized in the cells of Caryophyllales (red beets, opuntia, etc.). They are involved in the inactivation of reactive oxygen species and free radicals. The paper summarizes the data on the physical-chemical and pharmacological properties of betalains. Betalains eliminate the consequences of oxidative stress, effectively correct metabolic disorders in diabetes mellitus and abdominal obesity, and reduce the risk of cardiovascular diseases. A betalain-enriched diet has a wide range of anticancer effects. Betalains protect brain dopaminergic neurons from oxidative damage and reduce the severity of neurodegenerative disorders in Alzheimer’s and Parkinson’s disease. However, betalains are not stable enough to resist degradation during processing and storage of plant raw materials. Therefore, developing non-damaging technologies for betalain-containing treatment is highly relevant.

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The authors declare that there are no conflicts of interest present.