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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2023-3-89-91</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-2556</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICE OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>Анализ клинических случаев прогрессирования диабетической ретинопатии у беременных c сахарным диабетом 1-го типа</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of clinical progression of diabetic retinopathy in pregnant women with type 1 diabetes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3757-8351</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Помыткина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pomytkina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Помыткина Наталья Викторовна – к.м.н., врач-офтальмолог отделения лазерной хирургии</p><p>680033, г. Хабаровск, ул. Тихоокеанская, 211</p><p>тел. 8 (421) 290-56-17</p></bio><bio xml:lang="en"><p>Natalia V. Pomytkina, Cand. Sci. (Med.), ophthalmologist of the Department of Laser Surgery o</p><p>211 Tikhookeanskaya str., Khabarovsk, 680033, Russia</p><p>tel. 8 (421) 290-56-17</p></bio><email xlink:type="simple">naukakhvmntk@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НМИЦ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Минздрава России, Хабаровский филиал;&#13;
Дальневосточный государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch;&#13;
Far Eastern State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>23</day><month>09</month><year>2023</year></pub-date><volume>0</volume><issue>3</issue><fpage>89</fpage><lpage>91</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Помыткина Н.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Помыткина Н.В.</copyright-holder><copyright-holder xml:lang="en">Pomytkina N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/2556">https://www.tmj-vgmu.ru/jour/article/view/2556</self-uri><abstract><p>Представлены клинические случаи прогрессирования диабетической ретинопатии (ДР) у беременных с сахарным диабетом 1-го типа. При манифестации препролиферативной ДР установлено формирование фокального макулярного отека обоих глаз, с зонами неперфузии перимакулярной локализации. На обоих глазах проведена лазеркоагуляция сетчатки. Через один месяц обнаружен регресс макулярного отека на левом глазу и геморрагических явлений на обоих глазах, но с появлением новых зон неперфузии. Прогрессирование ДР во время беременности и в послеродовом периоде определяется рядом факторов: компенсацией сахарного диабета, стабилизацией ретинопатии, наличием сопутствующей патологии. При агрессивном течении пролиферативной ДР выявлена локальная тракционная отслойка сетчатки, частичный гемофтальм левого глаза. Проведены три этапа панретинальной лазеркоагуляции обоих глаз, эндовитреальное вмешательство с силиконовой тампонадой на левом глазу. В 28 недель беременности на правом глазу наблюдалось прогрессирование ретинальной неоваскуляризации, обширные зоны неперфузии в заднем полюсе. Проведено уплотнение зон лазеркоагуляции сетчатки на правом глазу.</p></abstract><trans-abstract xml:lang="en"><p>This article presents clinical cases of progression of diabetic retinopathy (DR) in pregnant women with type 1 diabetes. The manifestation of pre-proliferative DR was related to the formation of focal macular edema in both eyes with nonperfusion areas of perimacular localization. Both eyes underwent laser coagulation of the retina. Following one month, the regression of macular edema in the left eye and hemorrhagic phenomena in both eyes with the appearance of new nonperfusion areas were observed. DR progression during pregnancy and in the postpartum period is determined by a number of factors, including compensation for diabetes mellitus, stabilization of retinopathy, and the presence of concomitant pathologies. In the aggressive course of proliferative DR, local traction retinal detachment and partial hemophthalmos of the left eye were revealed. Three stages of panretinal laser coagulation of both eyes were conducted, along with an endovitreal intervention with silicone tamponade on the left eye. At 28 weeks of gestation, progression of retinal neovascularization with extensive areas of nonperfusion in the posterior pole was observed in the right eye. Compaction of the laser coagulation areas of the retina in the right eye was performed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>прогрессирование диабетической ретинопатии</kwd><kwd>лазеркоагуляция сетчатки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnancy</kwd><kwd>diabetic retinopathy progression</kwd><kwd>retinal laser photocoagulation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chew EY, Mills JL, Metzger BE, Remaley NA, Jovanovic-Peterson L, Knopp RH, Conley M, Rand L, Simpson JL, Holmes LB, Aarons JH. 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