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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2024-1-72-74</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-2694</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICE OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>Летальный исход случая геморрагической лихорадки с почечным синдромом</article-title><trans-title-group xml:lang="en"><trans-title>Fatal case of haemorrhagic fever with renal syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5166-5569</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попов Александр Федорович – д-р мед. наук, профессор кафедры эпидемиологии и военной эпидемиологии </p><p>690002, Владивосток, пр-т Острякова, 2   тел.: +7 (914) 704-56-20 </p></bio><bio xml:lang="en"><p>Alexander F. Popov, Dr. Sci. (Med.), Professor of the Department of Epidemiology and Military Epidemiology </p><p>2 Ostryakova Ave, Vladivostok, 690002   phone: +7 (914) 704-56-20 </p></bio><email xlink:type="simple">doctor.popov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванис</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanis</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Верхотурова</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Verkhoturova</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафронова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Safronova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кабанцева</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kabantsevа</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ехлаков</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yehlakov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlov</surname><given-names>V. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет ; Дальневосточный федеральный университет ; Дальневосточный филиал Государственного научно-исследовательского испытательного института военной медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University ; Far Eastern Federal University ; Far Eastern Branch of the State Research and Testing Institute of Military Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Краевая клиническая инфекционная больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Infectious Diseases Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Владивостокская клиническая больница № 2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Vladivostok Clinical Hospital № 2</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>18</day><month>05</month><year>2024</year></pub-date><volume>0</volume><issue>1</issue><fpage>72</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Попов А.Ф., Иванис В.А., Верхотурова В.И., Сафронова Е.В., Кабанцева Т.А., Ехлаков С.И., Павлов В.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Попов А.Ф., Иванис В.А., Верхотурова В.И., Сафронова Е.В., Кабанцева Т.А., Ехлаков С.И., Павлов В.А.</copyright-holder><copyright-holder xml:lang="en">Popov A.F., Ivanis V.A., Verkhoturova V.I., Safronova E.V., Kabantsevа T.A., Yehlakov S.I., Pavlov V.А.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/2694">https://www.tmj-vgmu.ru/jour/article/view/2694</self-uri><abstract><p>Дальневосточный федеральный округ является эпидемическим очагом ГЛПС (геморрагическая лихорадка с почечным синдромом), где заболеваемость обусловливают два ортохантавируса: Хантаан (в том числе его вариант Амур) и Сеул. В Приморском крае средний многолетний уровень заболеваемости за 13 лет (2011–2023 гг.) составил 2,7% (в отдельные годы до 4,4% на 100 тыс. населения), а летальность – 3,2% (в 2018 году – 9,1%). Распределение клинических форм заболевания за последние 13 лет показало, что преобладает среднетяжелая форма (66%), тяжелые формы составили около 30% всех краевых случаев. Приведен клинический случай тяжелого течения геморрагической лихорадки с почечным синдромом с летальным исходом молодого мужчины без сопутствующей патологии.</p></abstract><trans-abstract xml:lang="en"><p>The Far Eastern Federal District comprises an epidemic focus of hemorrhagic fever with renal syndrome (HFRS), where the incidence is determined by two orthohantaviruses: Hantaan (including its variant Amur) and Seoul. In Primorsky Krai, the average long-term incidence rate for 13 years (2011–2023) accounted for 2.7% (in some years up to 4.4% per 100 thousand population), and the mortality rate comprised 3.2% (9.1% in 2018). The distribution of clinical forms of the disease over the past 13 years revealed the prevalence of its moderate forms (66%), severe forms accounted for about 30% of all cases. The study presents a clinical case of severe course of HFRS with lethal outcome in a young male with no concomitant pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>геморрагическая лихорадка с почечным синдромом</kwd><kwd>инфекционно-токсический шок</kwd><kwd>гемодиализ</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hemorrhagic fever with renal syndrome</kwd><kwd>infectious-toxic shock</kwd><kwd>hemodialysis</kwd><kwd>clinical case</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tkachenko EA, Ishmukhametov АА, Dzagurova ТК, Bernshtein АD, Morozov VG, Siniugina AA, Kurashova SS, Balkina AS, Tkachenko PE, Kruger DH, Klempa B. 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