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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2025-2-45-49</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-2925</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Прогностическая модель летальности на основе логистической регрессии лабораторных показателей</article-title><trans-title-group xml:lang="en"><trans-title>Predictive model of mortality based on logistic regression of laboratory indicators</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-1622-0511</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мозоль</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mozol</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мозоль Андрей Николаевич – заместитель главного врача по медицинской части</p><p>692701, Приморский край, Хасанский МО, п.г.т. Славянка, ул. Молодежная, 3</p></bio><bio xml:lang="en"><p>Andrei N. Mozol, Deputy Chief Physician for Medical Affairs</p><p>Molodezhnaya st., Slavyanka urban-type settlement, Khasansky MO, Primorsky Krai, 692701</p></bio><email xlink:type="simple">usteerus@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Хасанская центральная районная больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Khasanskaya Central District Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>11</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>45</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мозоль А.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Мозоль А.Н.</copyright-holder><copyright-holder xml:lang="en">Mozol A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/2925">https://www.tmj-vgmu.ru/jour/article/view/2925</self-uri><abstract><p>Цель: разработка и валидация математической модели для прогнозирования риска летальных исходов на основе лабораторных показателей крови и мочи пациентов. Материалы и методы. В исследовании проанализированы клинические данные пациентов, включая результаты лабораторных исследований крови и мочи. Для создания модели использовались методы математического моделирования и статистического анализа. Результаты. Разработана прогностическая модель, демонстрирующая высокую точность в определении риска неблагоприятного исхода. Модель основана на доступных лабораторных показателях и может быть легко интегрирована в клиническую практику. Заключение. Предложенная математическая модель представляет собой эффективный инструмент для ранней диагностики риска летальных исходов. Практическая значимость исследования определяется возможностью использования разработанной модели в различных областях клинической медицины для оптимизации лечебно-диагностического процесса.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To develop and validate a mathematical model for predicting the risk of mortality based on patients’ laboratory indicators from blood and urine tests. Materials and methods. Clinical data of patients, including laboratory test results of blood and urine, were analyzed. Mathematical modeling and statistical analysis methods were used to develop the predictive model. Results. A predictive model demonstrating high accuracy in assessing the risk of adverse outcomes was developed. The model is based on readily available laboratory indicators and can be easily integrated into clinical practice. Conclusion. The proposed mathematical model represents an effective tool for early diagnosis of mortality risk. The practical significance of the study lies in the potential application of the developed model across various fields of clinical medicine to optimize the diagnostic and therapeutic process</p></trans-abstract><kwd-group xml:lang="ru"><kwd>прогностическая модель летальности</kwd><kwd>математическое моделирование смерти</kwd><kwd>риск летального исхода</kwd></kwd-group><kwd-group xml:lang="en"><kwd>predictive mortality model</kwd><kwd>mathematical modeling of mortality</kwd><kwd>risk of fatal outcome</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Автор заявляет о финансировании проведенного исследования из собственных средств.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bahadori M, Soltani M, Soleimani M, Bahadori M Statistical modeling in healthcare: shaping the future of medical research and healthcare delivery. ResearchGate. 2023;9(25):431–446. doi: 10.4018/979-8-3693-0876-9.ch025</mixed-citation><mixed-citation xml:lang="en">Bahadori M, Soltani M, Soleimani M, Bahadori M Statistical modeling in healthcare: shaping the future of medical research and healthcare delivery. ResearchGate. 2023;9(25):431–446. doi: 10.4018/979-8-3693-0876-9.ch025</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Toma M, Ong C Predictive modeling in medicine. MDPI. 2023;3(2):590–601. doi: 10.3390/encyclopedia3020042</mixed-citation><mixed-citation xml:lang="en">Toma M, Ong C Predictive modeling in medicine. MDPI. 2023;3(2):590–601. doi: 10.3390/encyclopedia3020042</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Заворотний О.О., Зиновьев Е.В., Костяков Д.В. Возможности прогнозирования летального исхода тяжелообожженных на основе методов регрессионного анализа. Вестник хирургии имени И.И. Грекова. 2020;179(5):21–29.</mixed-citation><mixed-citation xml:lang="en">Zavorotniy OO, Zinoviev EV, Kostyakov D.V. Predicting for mortality rate using regression analysis in patient with burn injury. Grekov's Bulletin of Surgery. 2020;179(5):21–29 (In Russ.) doi: 10.24884/0042-4625-2020-179-5-21-29</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Hooft L, Schuit E, Debray TPA Prediction models for cardiovascular disease risk in the general population: systematic review damen. Center for health sciences and primary care, university medical center. 2016;353:i2416. doi: 10.1136/bmj.i2416</mixed-citation><mixed-citation xml:lang="en">Hooft L, Schuit E, Debray TPA Prediction models for cardiovascular disease risk in the general population: systematic review damen. Center for health sciences and primary care, university medical center. 2016;353:i2416. doi: 10.1136/bmj.i2416</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Chao HY, Wu CC, Singh A, Shedd A, Wolfshohl J, Chou EH, Huang YC, Chen KF Using machine learning to develop and validate an in-hospital mortality prediction model for patients with suspected sepsis. Biomedicines. 2022;10(4):802. doi: 10.3390/biomedicines10040802</mixed-citation><mixed-citation xml:lang="en">Chao HY, Wu CC, Singh A, Shedd A, Wolfshohl J, Chou EH, Huang YC, Chen KF Using machine learning to develop and validate an in-hospital mortality prediction model for patients with suspected sepsis. Biomedicines. 2022;10(4):802. doi: 10.3390/biomedicines10040802</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Wendland Ph, Schmitt V, Zimmermann J Machine learning models for predicting severe COVID-19 outcomes in hospitals. Informatics in medicine unlocked. 2023;37:101188. doi: 10.1016/j.imu.2023.101188</mixed-citation><mixed-citation xml:lang="en">Wendland Ph, Schmitt V, Zimmermann J Machine learning models for predicting severe COVID-19 outcomes in hospitals. Informatics in medicine unlocked. 2023;37:101188. doi: 10.1016/j.imu.2023.101188</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Насар А.Н., Мадай Д.Ю. Объективная оценка тяжести сочетанной черепно-лицевой травмы (обзор). Кубанский научный медицинский вестник. 2020;27(5):144–162.</mixed-citation><mixed-citation xml:lang="en">Nassar AI., Madai DYu. Scoring models for the severity of combined craniofacial trauma (a review). Kuban Scientific Medical Bulletin. 2020;27(5):144–162 (In Russ.) doi: 10.25207/1608-6228-2020-27-5-144-162</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
