pmjТихоокеанский медицинский журналPacific Medical Journal1609-1175TGMU10.34215/1609-1175-2025-4-16-22pmj-3013Research ArticleОБЗОРЫREVIEWSПарапротезная инфекция искусственного аортального трансплантата: современное состояние проблемыProsthetic aortic graft infection: A review of the current situationМарчукМ. В.MarchukM. V.

Владивосток

Vladivostok

https://orcid.org/0009-0002-3179-2963СоболевскаяО. А.SobolevskayaO. A.

Соболевская Ольга Анатольевна – канд. мед наук, доцент института хирургии

690002 Владивосток, ул. Отлогая, 10, кв. 39

Olga A. Sobolevskaya, Cand. Sci. (Med.), Assistant Professor at the Institute of Surgery

10, Apt. 39 Otlogaya str., Vladivostok, 690002, Russia

osobolevskaya@mail.ruРаповкаВ. Г.RapovkaV. G.

Владивосток

Vladivostok

Приморская краевая клиническая больница № 1РоссияPrimorsky Regional Clinical Hospital No. 1Russian FederationТихоокеанский государственный медицинский университетРоссияPacific State Medical UniversityRussian Federation202515022026041622Copyright © Марчук М.В., Соболевская О.А., Раповка В.Г., 20262026Марчук М.В., Соболевская О.А., Раповка В.Г.Marchuk M.V., Sobolevskaya O.A., Rapovka V.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tmj-vgmu.ru/jour/article/view/3013

В статье рассматривается разнообразие причин развития парапротезной инфекции искусственного аортального трансплантата как наиболее опасного осложнения после сосудистых реконструкций с применением синтетических сосудистых протезов. Осложнение рассматривается как процесс, имеющий многофакторный патогенез и возникающий как результат комбинированного влияния периоперационных факторов и факторов риска со стороны пациента. Обсуждаются все известные методы лабораторной и инструментальной диагностики этого осложнения, а также приведены клинические классификации в соответствии с рекомендациями Сотрудничества по лечению инфекции аортального трансплантата. Поскольку в настоящее время нет стандартизованных методов лечения пациентов с парапротезной инфекцией, что предопределено разнообразием клинических форм, обусловленных распространенностью процесса, вирулентностью микробного агента, реакцией пациента на септический процесс, различным уровнем клиник, занимающихся оказанием помощи пациентам с данной патологией, целью данного обзора является анализ более 40 литературных источников о причинах развития парапротезной инфекции искусственного аортального трансплантата, методах диагностики и комплексного лечения за последние 15 лет.

The article discusses various causes of prosthetic infection affecting synthetic aortic grafts in patients who have undergone vascular reconstruction using synthetic vascular prostheses. Considered a highly dangerous complication, this infection is regarded as a process with multifactorial pathogenesis resulting from the combined impact of intraoperative factors and patient risk factors. All established methods of laboratory and instrumental diagnosis of this complication are discussed; clinical classifications are also provided in accordance with the recommendations of the Management of Aortic Graft Infection Collaboration (MAGIC). Standardized methods for treating patients with prosthetic infection remain undefined due to the diversity of its clinical forms, which are associated with the extent of the process, the virulence of the microbial agent, the patient's response to the septic process, and the varying levels of expertise among clinics providing care to patients with this pathology. Accordingly, this study aims to review more than 40 publications on the causes of prosthetic aortic graft infection, diagnostic methods, and comprehensive treatment over the past 15 years.

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The authors declare that there are no conflicts of interest present.