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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/PmJ1609-1175.2019.3.33-36</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-322</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Оценка потенциальной эпидемической опасности заболеваемости клещевыми инфекциями в Республике Алтай</article-title><trans-title-group xml:lang="en"><trans-title>ASSESSMENT OF POTENTIAL BIOLOGICAL HAZARD OF TICKBORNE DISEASES MORBIDITY IN THE REPUBLIC OF ALTAI</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Широкоступ</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shirokostup</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент кафедры эпидемиологии, микробиологии и вирусологии </p><p>656038, г. Барнаул, пр-т Ленина, 40</p></bio><bio xml:lang="en"><p>40 Lenina Ave. Barnaul 656038 Russian Federation</p></bio><email xlink:type="simple">shirokostup@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукьяненко</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukyanenko</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры эпидемиологии, микробиологии и вирусологии </p><p>656038, г. Барнаул, пр-т Ленина, 40</p></bio><bio xml:lang="en"><p>40 Lenina Ave. Barnaul 656038 Russian Federation</p></bio><email xlink:type="simple">natvalluk@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баландович</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balandovich</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры гигиены, основ экологии и безопасности жизнедеятельности, директор Института гигиены труда и промышленной экологии  </p><p>656038, г. Барнаул, пр-т Ленина, 40</p></bio><bio xml:lang="en"><p>40 Lenina Ave. Barnaul 656038 Russian Federation</p></bio><email xlink:type="simple">dr.balandovich@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафьянова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Safyanova</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, заведующая кафедрой эпидемиологии, микробиологии и вирусологии</p><p>656038, г. Барнаул, пр-т Ленина, 40</p></bio><bio xml:lang="en"><p>40 Lenina Ave. Barnaul 656038 Russian Federation</p></bio><email xlink:type="simple">tvsafyanova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Алтайский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Altai State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2019</year></pub-date><volume>0</volume><issue>3</issue><fpage>33</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Широкоступ С.В., Лукьяненко Н.В., Баландович Б.А., Сафьянова Т.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Широкоступ С.В., Лукьяненко Н.В., Баландович Б.А., Сафьянова Т.В.</copyright-holder><copyright-holder xml:lang="en">Shirokostup S.V., Lukyanenko N.V., Balandovich B.A., Safyanova T.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/322">https://www.tmj-vgmu.ru/jour/article/view/322</self-uri><abstract><p>Цель: оценка динамики эпидемической опасности заболеваемости клещевым энцефалитом и другими клещевыми трансмиссивными природно-очаговыми инфекциями в Республике Алтай. Материал и методы. Использованы статистические данные санитарно-эпидемиологической службы Республики Алтай. Расчет прогностических значений заболеваемости осуществлялся посредством построения нейросетевой модели методом прогнозирования временного ряда. Результаты. Ранжирование административных территорий позволило разделить районы республики на три группы: с высоким (от 25 на 100 тыс. населения и более), средним (15–24,9 на 100 тыс. населения) и низким (до 14,9 на 100 тыс. населения) уровнями заболеваемости клещевым энцефалитом. В группу с высокой заболеваемостью были отнесены Турочакский и Онгудайский районы, в группу с низкой заболеваемостью – Кош-Агачский район. Заключение. В нейросетевой модели было установлено, что в течение 5-летнего периода (2013–2017) прогностические уровни заболеваемости клещевым энцефалитолм превышали фактические со средней относительной ошибкой ±0,1 и в среднем равнялись 9,18 на 100 тыс. населения. В течение данного периода разница абсолютных значений прогностического и фактического показателей составила десять случаев (т.е. по два случая в год). Разница между этими показателями с учетом небольшой средней относительной ошибки может быть объяснена неучтенными случаями клещевых инфекций, которые по клиническим проявлениям сходы с клещевым энцефалитом и учитываются по МКБ-10 как «лихорадка неясного происхождения» (R50).</p></abstract><trans-abstract xml:lang="en"><p>Objective: assessment of dynamics of biological hazard of morbidity of tickborne encephalitis and other tickborne transmissible feral herd infections in the Republic of Altai.Methods: Statistical data of disease control and prevention service of the Republic of Altai was used. Calculation of prognostic value of incidence was done by building of connectionist model with a time series forecasting method.Results: Ranking of administrative territories allowed us to divide Republic districts into three groups: with high (from 25 per 100 thousand population), medium (15–24.9 per 100 thousand population), and low (up to 14.9 per 100 thousand population) levels of incidence of tickborne encephalitis. The Turochaksky and Ongudaysky districts were assigned to the group with a high incidence, and the Kosh-Agachsky area was assigned to the group with a low incidence.Conclusions: Using the connectionist model it was established that during 5-year period (2013–2017) forecasting levels of tickborne encephalitis incidence exceeded the actual ones with average relative error ±0.1 and were 9.18 per 100 thousand population on average. During this period the difference in absolute values of prognostic and actual values was ten cases (i.e. two cases per year). The difference between these indicators, taking into account the small average relative error, can be explained by unaccounted cases of tickborne infections, which are clinical manifestations of tickborne encephalitis and are considered by ICD-10 as “fever of unknown origin” (R50).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>клещи</kwd><kwd>трансмиссивные инфекции</kwd><kwd>эпидемическая опасность заражения</kwd><kwd>картограммы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ticks</kwd><kwd>transmissible infections</kwd><kwd>biological hazard infection</kwd><kwd>cartogram</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Морозова О.В. Проблемы и перспективы профилактики, диагностики и лечения клещевого энцефалита // Российский медицинский журнал. 2014. № 6. С. 26–31.</mixed-citation><mixed-citation xml:lang="en">Morozova O.V. 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