pmjТихоокеанский медицинский журналPacific Medical Journal1609-1175TGMU10.34215/1609-1175-2019-4-88-90pmj-392Research ArticleМЕТОДИКАMETHODSСовершенствование диагностического алгоритма при гастроинтестинальной форме пищевой аллергии у младенцевImproved diagnostic algorithm for gastrointestinal food allergy in infantshttps://orcid.org/0000-0003-1173-7553ДенисовМ. Ю.DenisovM. Yu.

Денисов Михаил Юрьевич – доктор медицинских наук, профессор кафедры акушерства и гинекологии Института медицины и психологии

630090, г. Новосибирск, ул. Пирогова, 1

Mikhail Yu. Denisov, MD, PhD, professor, Department of Obstetrics and Gynecology, Institute of Medicine and Psychology

1 Pirogova St., Novosibirsk, 630090

mi.den@mail.ruГильдЕ. В.GildE. V.Новосибирский государственный университетРоссияNovosibirsk State UniversityRussian Federation201928122019048890Copyright © Денисов М.Ю., Гильд Е.В., 20192019Денисов М.Ю., Гильд Е.В.Denisov M.Y., Gild E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tmj-vgmu.ru/jour/article/view/392Цель

Цель: усовершенствовать неинвазивный диагностический алгоритм (НДА) выявления пищевой аллергии (ПА) у детей первых месяцев жизни.

Материал и методы

Материал и методы. Проведено клинико-анамнестическое обследование и последующее динамическое наблюдение за 26 детьми в возрасте от 1 недели до 9 месяцев, поступивших с жалобами на колики, диарею, вздутие живота и кожные высыпания. Первичный скрининг проведен по системе CoMiSS, далее целенаправленно собраны данные анамнеза согласно НДА.

Результаты

Результаты. У 34,6 % младенцев, благодаря усовершенствованному НДА, на раннем этапе диагностирована ПА. Динамическое наблюдение позволило говорить о наличии ПА у 46,1 % пациентов.

Заключение

Заключение. Опросник показал высокую клиническую эффективность и специфичность, превышающую существующие аналоги для неинвазивной диагностики синдрома мальабсорбции у младенцев.

Objective

Objective: The objective is to improve non-invasive diagnostic algorithm (NDA) to identify food allergy (FA) in infants since their first months of live.

Methods

Methods: We have done clinical and anamnestic examination and subsequent follow-up of 26 infants aged from 1 week old to 9 months old having admitted with complaints about colics, diarrhea, abdominal distension and skin rashes. Primary screening was performed using CoMiss tool, then anamnesis data was collected according NDA.

Results

Results: FA was diagnosed in 34.6 % of infants due to improved NDA. Case follow-up suggested the presence of FA in 46.1% of patients.

Conclusions

Conclusions: The questionnaire showed a high clinical effectiveness and uniqueness, exceeding current alternatives for non-invasive diagnostics of malabsorption syndrome in infants.

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The authors declare that there are no conflicts of interest present.