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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2020-1-28-31</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-411</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Сроки контаминации ожоговых ран нозокомиальной флорой</article-title><trans-title-group xml:lang="en"><trans-title>The terms of the burn wounds contamination with the nosocomial flora</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0712-0422</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митряшов</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitryashov</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант департамента клинической медицины,</p><p>690950, г. Владивосток, ул. Суханова, 8</p></bio><bio xml:lang="en"><p>MD, postgraduate student, Department of Clinical Medicine, </p><p>8 Sukhanova St., Vladivostok, 690950</p></bio><email xlink:type="simple">mark498@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Охотина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Okhotina</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. биол. наук, преподаватель Международной лингвистической школы,</p><p>690106, Владивосток, Партизанский пр-т, 44)</p></bio><bio xml:lang="en"><p>PhD, </p><p>44 Partizansky Ave., Vladivostok, 690106</p></bio><email xlink:type="simple">okhotina@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шмагунова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shmagunova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-бактериолог,</p><p>690022, г. Владивосток, пр-т 100 лет Владивостоку, 161</p></bio><bio xml:lang="en"><p>MD, </p><p>161 Sto Let Vladivostoku Ave., Vladivostok, 690022</p></bio><email xlink:type="simple">shmagunov_v@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4024-7449</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселев</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselev</surname><given-names>A. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент департамента клинической медицины,</p><p>690950, г. Владивосток, ул. Суханова, 8</p></bio><bio xml:lang="en"><p>MD, PhD, associate professor, Department of Clinical Medicine, </p><p>8 Sukhanova St., Vladivostok, 690950</p></bio><email xlink:type="simple">kiselev_artem@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1182-7551</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Усов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Usov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, заведующий кафедрой департамента клинической медицины,</p><p>690950, г. Владивосток, ул. Суханова, 8</p></bio><bio xml:lang="en"><p>MD, PhD, head of Department of Clinical Medicine, </p><p>8 Sukhanova St., Vladivostok, 690950</p></bio><email xlink:type="simple">vict-s-vl-d@ya-dex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Школа биомедицины Дальневосточного федерального университета</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far Eastern Federal University, School of biomedicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Владивостокский государственный университет экономики и сервиса</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok State University of Economics and Service</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Дальневосточный окружной медицинский центр ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far Eastern Regional Medical Centre of FMBA</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2020</year></pub-date><volume>0</volume><issue>1</issue><fpage>28</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Митряшов К.В., Охотина С.В., Шмагунова Е.В., Киселев А.Ю., Усов В.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Митряшов К.В., Охотина С.В., Шмагунова Е.В., Киселев А.Ю., Усов В.В.</copyright-holder><copyright-holder xml:lang="en">Mitryashov K.V., Okhotina S.V., Shmagunova E.V., Kiselev A.U., Usov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/411">https://www.tmj-vgmu.ru/jour/article/view/411</self-uri><abstract><sec><title>Цель</title><p>Цель: анализ динамики микробной обсемененности ожоговых ран и объективная оценка маркеров внутрибольничной инфекции (ВБИ) в  разные сроки госпитализации.</p></sec><sec><title>Материал и  методы</title><p>Материал и  методы. Проведен анализ 617 микробиологических проб с поверхности ожоговых ран от 515 больных в срок от первых до девятых суток после травмы. Определяли присутствие грамотрицательных бактерий P. aeruginosa и  A. baumannii, полирезистентных микроорганизмов и  микробных ассоциаций. Для идентификации возбудителей использовали спектрофотометрический, для оценки микробной обсемененности ран – чашечный метод.</p></sec><sec><title>Результаты</title><p>Результаты. В процессе лечения происходила смена возбудителей, ассоциированная с длительностью пребывания в стационаре. С увеличением срока госпитализации возрастала степень микробного загрязнения ран, частота присутствия грамотрицательных бактерий, полирезистентных микроорганизмов и микробных ассоциаций.</p></sec><sec><title>Заключение</title><p>Заключение. Наибольшая выраженность всех признаков ВБИ приходится на 3–4-е сутки пребывания в ожоговом стационаре. Эти сроки можно считать началом активной контаминации ожоговых ран нозокомиальной флорой. Для предотвращения этого необходимо как можно раньше, со 2–3-х суток с момента госпитализации применять активную тактику лечения ожоговых ран и закрытия ожоговых поверхностей. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. The study objective it to analyze the dynamics of microbial content of burn wounds and to assess the markers of hospital-acquired infection (HAI) in different periods of hospitalization.</p></sec><sec><title>Methods</title><p>Methods: 617 microbiological samples from the surface of burn wounds of 515 patients in the period from the first to ninth days after the injury were analyzed. The presence of gramnegative bacteria Pseudomonas aeruginosa and Acinetobacter baumannii, multiresistant microorganisms and microbial associations was determined. Spectrophotometry was used to identify pathogens and plate method was used to assess microbial content of wounds.</p></sec><sec><title>Results</title><p>Results: During treatment, there was change of pathogens associated with duration of stay in the hospital. With an increase in hospitalization, the degree of microbial contamination of wounds, the rate of gram-negative bacteria, multiresistant microorganisms, and microbial associations increased.</p></sec><sec><title>Conclusions</title><p>Conclusions: The greatest severity of all signs of nosocomial infection occurs on the 3–4th day of hospitalization in a burn care facility. This period can be considered ad a start of active contamination of burn wounds with nosocomial flora. To prevent this, it is necessary as early as possible, from 2–3 days after hospitalization to apply active strategy for treating burn wounds and closing burn surfaces. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ожоговая травма</kwd><kwd>внутрибольничные инфекции</kwd><kwd>грамотрицательные бактерии</kwd><kwd>полирезистентные микроорганизмы</kwd><kwd>микробные ассоциации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>burn injury</kwd><kwd>nosocomial infections</kwd><kwd>gram-negative bacteria</kwd><kwd>multiresistant microorganisms</kwd><kwd>microbial associations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алексеев А.А., Крутиков М.Г., Яковлев В.П. Ожоговая инфекция. Этиология, патогенез, диагностика, профилактика и лечение. М.: Вузовская книга, 2010. 416 с.</mixed-citation><mixed-citation xml:lang="en">Alekseyev AA, Krutikov MG, Yakovlev VP. 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