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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2020-1-64-67</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-420</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕТОДИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>METHODS</subject></subj-group></article-categories><title-group><article-title>Эндоскопическая подслизистая диссекция в толстой кишке: результаты первых 200 вмешательств</article-title><trans-title-group xml:lang="en"><trans-title>Colorectal endoscopic submucosal dissection: The results of the first 200 procedures</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7023-082X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Халин</surname><given-names>К. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Khalin</surname><given-names>K. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач эндоскопического отделения, 690003, г. Владивосток, ул. Верхне-Портовая, 25,</p><p>аспирант Института хирургии, 690002, г. Владивосток, пр-т Острякова, 2</p></bio><bio xml:lang="en"><p>MD, 25 Verhne-Portovaya St., Vladivostok, 690003;</p><p>postgraduate student, 2 Ostryakova Ave., Vladivostok, 690002</p></bio><email xlink:type="simple">khalin_kd@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агапов</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Agapov</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, врач эндоскопического отделения,</p><p>198255, г. Санкт-Петербург, пр-т Ветеранов, 56</p></bio><bio xml:lang="en"><p>MD, PhD, 56 Veteranov Ave., Saint Petersburg, 198255</p></bio><email xlink:type="simple">misha_agapov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зверева</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvereva</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>зав. патологоанатомическим отделением,</p><p>690003, г. Владивосток, ул. Верхне-Портовая, 25</p></bio><bio xml:lang="en"><p>MD, chief of pathology department,</p><p>25 Verhne-Portovaya St., Vladivostok, 690003</p></bio><email xlink:type="simple">jule91@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Огурчёнок</surname><given-names>Н. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Ogurchyenok</surname><given-names>N. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач патолого-анатомического отделения,</p><p>690003, г. Владивосток, ул. Верхне-Портовая, 25</p></bio><bio xml:lang="en"><p>MD, pathologist, 25 Verhne-Portovaya St., Vladivostok, 690003</p></bio><email xlink:type="simple">murashka1992@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыжков</surname><given-names>Е. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Ryzhkov</surname><given-names>E. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>зав. эндоскопическим отделением,</p><p>690003, г. Владивосток, ул. Верхне-Портовая, 25</p></bio><bio xml:lang="en"><p>MD, chief of endoscopic department,</p><p>25 Verhne-Portovaya St., Vladivostok, 690003</p></bio><email xlink:type="simple">magistr9lifes@bk.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барсуков</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Barsukov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач,</p><p>690003, г. Владивосток, ул. Верхне-Портовая, 25 </p></bio><bio xml:lang="en"><p>MD, endoscopist, 25 Verhne-Portovaya St., Vladivostok, 690003</p></bio><email xlink:type="simple">abarsukov2000@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0472-9504</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стегний</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Stegniy</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., чл.-корр. РАН, директор Института хирургии, 690002, г. Владивосток, пр-т Острякова, 2; заведующий центром хирургии Медицинского центра, 690950, г. Владивосток, ул. Суханова, 8</p></bio><bio xml:lang="en"><p>MD, PhD, professor, member of the Russian Academy of Sciences, Director of the Surgery Institute, 2 Ostryakova Ave., Vladivostok, 690002;</p><p>head of the Surgery Department, 8 Sukhanova St., Vladivostok, 690950</p></bio><email xlink:type="simple">kstegniy@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клиническая больница «РЖД-Медицина»;&#13;
Тихоокеанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Private Clinical Hospital “RZhD-Medicine”;&#13;
Pacific State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городской клинический онкологический диспансер</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Oncological Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Клиническая больница «РЖД-Медицина»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Private Clinical Hospital “RZhD-Medicine”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет;&#13;
Дальневосточный федеральный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University;&#13;
Far Eastern Federal University Medical Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2020</year></pub-date><volume>0</volume><issue>1</issue><fpage>64</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Халин К.Д., Агапов М.Ю., Зверева Л.В., Огурчёнок Н.Е., Рыжков Е.Ф., Барсуков А.С., Стегний К.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Халин К.Д., Агапов М.Ю., Зверева Л.В., Огурчёнок Н.Е., Рыжков Е.Ф., Барсуков А.С., Стегний К.В.</copyright-holder><copyright-holder xml:lang="en">Khalin K.D., Agapov M.Y., Zvereva L.V., Ogurchyenok N.E., Ryzhkov E.F., Barsukov A.S., Stegniy A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/420">https://www.tmj-vgmu.ru/jour/article/view/420</self-uri><abstract><sec><title>Цель</title><p>Цель: анализ результатов эндоскопических подслизистых диссекций (ESD) новообразований толстой кишки, выполненных в одной клинике.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проанализированы данные о 207 ESD в толстой кишке за 2007–2019 гг. Оценивались время и скорость операций, количество резекций единым блоком и курабельных резекций, уровень осложнений и  изменение результатов по мере накопления опыта.</p></sec><sec><title>Результаты</title><p>Результаты. По локализации новообразования распределились следующим образом: правосторонние  – 48, левосторонние  – 71, прямокишечные  – 88. Средняя скорость подслизистой диссекции составила 13,5 мм2/мин., среднее время, затраченное на диссекцию одного квадратного сантиметра новообразования – 12,5 мин. Переход на петлевую ассистенцию потребовался в 35, конверсия на лапароскопическую резекцию – в 2 случаях. Курабельными, согласно критериям эндоскопической радикальности, были признаны 170 наблюдений (82,1%). По мере накопления опыта вмешательств, несмотря на рост числа опухолей правосторонней локализации, достоверно увеличилась скорость ESD, а количество перфораций и переходов на петлевую ассистенцию не изменилось.</p></sec><sec><title>Заключение</title><p>Заключение. ESD  – эффективная методика удаления новообразований толстой кишки, однако за период обучения специалист должен приобрести опыт не менее чем 100 вмешательств. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: The objective is to analyze the results of endoscopic submucosal dissections (ESDs) of large intestine tumors performed in one clinic.</p></sec><sec><title>Methods</title><p>Methods: Data on 207 ESDs in large intestine for 2007–2019 were analyzed. The duration and speed of surgical operation, the number of en block resections and curable resections, and the level of complications and change of results within gain in experience were assessed.</p></sec><sec><title>Results</title><p> Results: According to locations, tumors are divided as follows: right-sided – 48, left-sided – 71, rectal – 88. The average speed of submucosal dissection was 13.5 mm2/min.; the average time taken for dissection of one square centimeter of a tumor was 12.5 min. The conversion to loop assistance was required in 35 cases, conversion to a laparoscopic resection – in two cases. According to criteria of endoscopic radical operations, 170 (82.1%) cases were considered curable. As experience of operations was gaining, despite the increase in number of tumors of right-sided location, the speed of ESDs was significantly increased, and the number of perforations and conversions to loop assistance was not changed.</p></sec><sec><title>Conclusions</title><p>Conclusions: ESD is an effective method of large intestine tumor removal; however, during the training period, a professional should gain an experience in at least 100 operations. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>новообразования толстой кишки</kwd><kwd>эндоскопическая диссекция</kwd><kwd>осложнения</kwd><kwd>кривая обучения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>large intestine tumors</kwd><kwd>endoscopic dissection</kwd><kwd>complications</kwd><kwd>learning curve</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А.Д., Старинский В.В., Петрова Г.В., ред. 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