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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2020-2-90-91</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-462</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICE OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>Проявление В12-дефицитного состояния в полости рта</article-title><trans-title-group xml:lang="en"><trans-title>Manifestation of В12 deficiency in the oral cavity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4326-1801</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яценко</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Yatsenko</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яценко Анна Константиновна – канд. мед. наук, доцент института стоматологии</p><p>690002, г. Владивосток, пр-т Острякова, 2</p></bio><bio xml:lang="en"><p>Anna K. Yatsenko, MD, PhD, associate professor, Institute of Dentistry</p><p>1 Ostryakova Ave., Vladivostok, 690002</p></bio><email xlink:type="simple">annakonstt@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларионова</surname><given-names>Д. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Larionova</surname><given-names>D. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артюкова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Artyukova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плотникова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Plotnikova</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владивосток</p></bio><bio xml:lang="en"><p>Vladivostok</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2020</year></pub-date><volume>0</volume><issue>2</issue><fpage>90</fpage><lpage>91</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Яценко А.К., Ларионова Д.Б., Артюкова О.А., Плотникова И.Н., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Яценко А.К., Ларионова Д.Б., Артюкова О.А., Плотникова И.Н.</copyright-holder><copyright-holder xml:lang="en">Yatsenko A.K., Larionova D.B., Artyukova O.A., Plotnikova I.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/462">https://www.tmj-vgmu.ru/jour/article/view/462</self-uri><abstract><p>Представлен клинический случай патологического состояния полости рта, вызванного дефицитом в организме витамина В12 . У пациента 25 лет диагностированы атрофия участков слизистой оболочки рта (в т.ч. гунтеровский глоссит), гиперхромно-макроцитарная анемия, гастроэзофагеальная рефлюксная болезнь, атрофическая антральная гастропатия. Назначен курс инъекций цианокобаламина. При контрольном обследовании через три месяца лабораторных и клинических признаков рецидива заболевания не выявлено.</p></abstract><trans-abstract xml:lang="en"><p>A clinical case of pathological state of oral cavity caused by B12 deficiency is presented. The patient (25 y.o.) was diagnosed with atrophy of the oral mucosa (Hunter glossitis), hyperchromic microcytic anemia, gastroesophageal reflux disease, and atrophic antral gastritis. A course of injections of cyanocobalamin was prescribed. At the control examination after three months, laboratory and clinical symptoms of disease relapse were not detected.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>слизистая оболочка рта</kwd><kwd>цианокобаламин</kwd><kwd>анемия</kwd><kwd>гунтеровский глоссит</kwd><kwd>наблюдение из практики</kwd></kwd-group><kwd-group xml:lang="en"><kwd>oral mucosa</kwd><kwd>cyanocobalamin</kwd><kwd>anemia</kwd><kwd>Hunter glossitis</kwd><kwd>practice observation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Луцкая И.К. Проявления на слизистой оболочке полости рта заболеваний внутренних органов и СПИДа. Международные обзоры: клиническая практика и здоровье. 2013;6:32–53.</mixed-citation><mixed-citation xml:lang="en">Lutskaya IK. Manifestations of the oral mucosa of diseases of internal organs and AIDS. 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