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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.34215/1609-1175-2020-3-57-61</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-493</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Возрастные особенности организации микроциркуляторного русла бульбарной конъюнктивы</article-title><trans-title-group xml:lang="en"><trans-title>Age-related features of the organization of the microcirculatory bed of the bulbar conjunctiva</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1107-4561</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черток</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chertok</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующий кафедрой анатомии человека,</p><p>690002, г. Владивосток, пр-т Острякова, 2</p></bio><bio xml:lang="en"><p>MD, PhD, professor, head of the Department of Human Anatomy, </p><p>2, Ostryakova Ave., Vladivostok, 690002</p></bio><email xlink:type="simple">chertokv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Невзорова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nevzorova</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, директор Института терапии и инструментальной диагностики,</p><p>690002, г. Владивосток, пр-т Острякова, 2</p></bio><bio xml:lang="en"><p>MD, PhD, professor, head of the Institute of Intrinic Medicine and Instrumental diagnostics, </p><p>2, Ostryakova Ave., Vladivostok, 690002</p></bio><email xlink:type="simple">nevzorova@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савченко</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Savchenko</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студент лечебного факультета,</p><p>690002, г. Владивосток, пр-т Острякова, 2</p></bio><bio xml:lang="en"><p>student, </p><p>2, Ostryakova Ave., Vladivostok, 690002</p></bio><email xlink:type="simple">savalexbeast@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2224-8237</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирошниченко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Miroshnichenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, врач,</p><p>690922, г. Владивосток, бухта Аякс, 10</p></bio><bio xml:lang="en"><p>MD, PhD,</p><p>10 Ajax Bay, Russky Island, Vladivostok, 690922</p></bio><email xlink:type="simple">olgam.57@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларюшкина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Laryushkina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент кафедры анатомии человека,</p><p>690002, г. Владивосток, пр-т Острякова, 2</p></bio><bio xml:lang="en"><p>MD, PhD, associate professor, </p><p>2, Ostryakova Ave., Vladivostok, 690002</p></bio><email xlink:type="simple">alla.laryushkina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медицинский центр Дальневосточного федерального университета</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Center, Far Eastern Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2020</year></pub-date><volume>0</volume><issue>3</issue><fpage>57</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Черток В.М., Невзорова В.А., Савченко А.К., Мирошниченко О.В., Ларюшкина А.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Черток В.М., Невзорова В.А., Савченко А.К., Мирошниченко О.В., Ларюшкина А.В.</copyright-holder><copyright-holder xml:lang="en">Chertok V.M., Nevzorova V.A., Savchenko A.K., Miroshnichenko O.V., Laryushkina A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/493">https://www.tmj-vgmu.ru/jour/article/view/493</self-uri><abstract><sec><title>Цель</title><p>Цель: анализ возрастных изменений микроциркуляторного русла (МЦР) бульбарной конъюнктивы.</p></sec><sec><title>Материал и  методы</title><p>Материал и  методы. Обследовали 46 лиц обоего пола, разделенных с учетом рекомендаций ВОЗ на пять возрастных групп. Биомикроскопию бульбарной конъюнктивы проводили на немидриатической ретинальной камере TOPCON TRC-NW8F (Япония), полученные снимки обрабатывали на измерительном комплексе автоматизированной системы анализа изображе‑ ний ImageScope (Leica, Германия).</p></sec><sec><title>Результаты</title><p>Результаты. Средний диаметр артериол, артериоло-венуляный коэффициент (АВК) и  удельная плотность капилляров были наибольшими, а  диаметр венул  – наименьшим у  испытуемых 18–44 лет. На‑ иболее чувствительными индикаторами состояния МЦР оказались АВК и удельная плотность капилляров, значения которых в группе 45–59-летних были на 10–11% ниже, чем у лиц 18–24 и 25–44 лет. Различия по другим показателям между людьми 18–24 и 45–59 лет оказались несущественными. Между группами 60–74- и 75–86-летних участников ис‑ следования выраженные различия (около 18%) обнаружены лишь по удельной плотности капилляров: по сравнению с 18–24- и 45–59-летними данный показатель сокращался почти в 1,5 раза, АВК – только на треть, а изменения среднего диаметра артериол и венул не превышали 9–12%. У людей пожилого возраста чаще регистрировались спазм артериол, неравномерность их калибра, аваскулярные поля и другие нарушения структуры МЦР.</p></sec><sec><title>Заключение</title><p>Заключение. По мере старения организма в  МЦР бульбарной конъюнктивы увеличивается число атипичных сосудистых образований, сокращается диаметр артериол, уменьшаются АВК и удельная плотность капилляров, увеличивается диаметр венул. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: Analysis of age-related changes of microcirculatory bed of bulbar conjunctiva.</p></sec><sec><title>Methods</title><p>Methods: 46 individuals of both sexes, divided into 5 age groups according to WHO recommendations, were examined. Biomicroscopy of bulbar conjunctiva was performed using a non-mydriatic retinal camera TOPCON TRC-NW8F (Japan); the obtained images were processed with a mea‑ suring device of automated analysis system ImageScope (Leica, Germany).</p></sec><sec><title>Results</title><p>Results: The average diameter of arterioles, arterioleto-venule ratio (AVR) and specific density of capillaries were the largest, and the diameter of venules was the smallest among the subjects aged 18–44 years. The most sensitive indicators of the state of microcirculatory bed were AVR and the specific density of capillaries, the values of which in the group of 45–59-year-olds were 10–11% lower than in people aged 18–24 and 25–44 years. Differences in other indicators between people aged 18-24 and 45–59 years were not significant. Between the groups of 60–74 and 75–86-year-old participants of the study, pronounced differences (about 18%) were found only in the specific density of capillaries: compared with 18–24 and 45–59-year-olds, this indicator decreased by almost 1.5 times, AVR – only by a third, and changes in the average diameter of arterioles and venules did not exceed 9–12%. Elderly people more often demonstrated arteriolar spasm, their uneven caliber, avascular fields and other disorders of the structure of the micro‑ circulatory bed.</p></sec><sec><title>Conclusions</title><p>Conclusions: As the body ages, in the microcirculatory bed of the bulbar conjunctiva, the number of atypical vascular formations increases, the diameter of the arterioles decreases, the AVR and the specific density of capillaries decrease, the diameter of the venules increases. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>глаз</kwd><kwd>биомикроскопия бульбарной конъюнктивы</kwd><kwd>микроциркуляция</kwd><kwd>артериолы</kwd><kwd>венулы</kwd><kwd>возраст</kwd></kwd-group><kwd-group xml:lang="en"><kwd>eya</kwd><kwd>biomicroscopy of bulbar conjunctiva</kwd><kwd>microcirculation</kwd><kwd>arterioles</kwd><kwd>venules</kwd><kwd>age</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Козлов В.И. 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