Background. We studied the clinical course of pregnancy, status of the fetus and newborn in patients with chronic cytomegalovirus infection (CMV). Methods. A total of 150 pregnant women with chronic recurrent CMV infection (study group), out of which 50 backset was 9-14 weeks (1st subgroup), 50 - in the 15-21 week (2nd subgroup) and 50 - 22-37 weeks (third subgroup). A control group of 50 pregnant women seronegative for cytomegalovirus. Studied history, performed a physical, special obstetric and basic laboratory research. Determined the level progesterone in serum. Results. Showed an increase the frequency of complications of pregnancy in recurrent CMV infection. In the 1st subgroup threatening difficult pregnancy miscarriage (60%), primary (20%) and chronic (64%) and placental insufficiency and placenta previa (20%). In 23.5% of the mothers in this subgroup had children with hypotrophy and 22.5% - es in the brain). In the 2nd subgroup more often than in the 3rd diagnosed chronic placental insufficiency, polyhydramnios, oligohydramnios and fetal growth retardation. conclusions. Pregnancy complications which are shown with placental disorders and perinatal pathology in the newborn are formed at an early backset of CMV gestation period.