Background. In modern conditions exists necessity of forming in antenatal clinics complex of medical and organizational activities aimed to the optimizing the work to prevent pregnancy complications, reduce gynecological diseases, promoting healthy lifestyles. Methods. Conducted socio-hygienic research devoted to studying women attending antenatal clinics lifestyle, and the factors that influence it. Was questioned 488 women (365 pregnant women), statistical processing of questionnaires and set up an organizational experiments under conditions of the antenatal clinic. Results. Anonymous questioning of pregnant women showed their lack of medical activity (78.6%), the presence of bad habits before pregnancy (80.5%) and during pregnancy (18.9%), stressful situations (100%) and non-constructive behaviors (87.3%), and low awareness about the impact of different perinatal factors on the growth and development of their future children. With the opinion that the health of a child is formed, including under the influence of lifestyle parents-to-be disagreed over half (57.4%) of pregnant women, and only 43.7% of women rated their health as good. Conclusions. In order to optimize preventive work of antenatal clinic may be prompted to design a solution including a set of medical and organizational activities. It is necessary to create a new structural unit of antenatal clinic - the Cabinet of medical prevention, formation of an action plan aiming to the awareness of patients. Developed and tested a “School of prenatal pedagogics”, which can be widely implemented in the activities of women>s clinics.