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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-665</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Чувствительность микробиоты зубной бляшки к антисептикам в процессе ортодонтического лечения у детей</article-title><trans-title-group xml:lang="en"><trans-title>Sensitivity of microbiota of the tooth plaque to antiseptics during the orthodontic treatment in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чесноков</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chesnokov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чеснокова</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Chesnokova</surname><given-names>M. G.</given-names></name></name-alternatives><email xlink:type="simple">chesnokova_marin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миронов</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mironov</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Турчанинов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Turchaninov</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крига</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kriga</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинская фирма «Элита»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical firm “Elite”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Омская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Московский НИИ эпидемиологии и микробиологии им. Г.Н. Габичевского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Scientific Research Institute of Epidemiology and Microbiology named by G.N. Gabichevskiy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Управление Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека по Омской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Main Federal Service on supervision of protection of the consumers rights and human well-being in Omsk region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2014</year></pub-date><volume>0</volume><issue>3</issue><fpage>68</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чесноков В.А., Чеснокова М.Г., Миронов А.Ю., Турчанинов Д.В., Крига А.С., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Чесноков В.А., Чеснокова М.Г., Миронов А.Ю., Турчанинов Д.В., Крига А.С.</copyright-holder><copyright-holder xml:lang="en">Chesnokov V.A., Chesnokova M.G., Mironov A.Y., Turchaninov D.V., Kriga A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/665">https://www.tmj-vgmu.ru/jour/article/view/665</self-uri><abstract><p>Обследованы 47 пациентов 9-15 лет с дистальной окклюзией в процессе ортодонтического лечения. Из биоматериала зубной бляшки в 25 % наблюдений выделены грибы вида Candida albicans на фоне высокого содержания микроорганизмов, как кариесогенной, так и ассоциативной групп (Streptococcus, Enterococcus, Staphylococcus, Neisseria, Micrococcus, Corynebacterium, Klebsiella). Большинство штаммов продемонстрировали выраженную резистентность к 0,01 % мирамистину. Наиболее высокий уровень минимальной подавляющей концентрации по отношению к культурам S. aureus, S. epidermidis, S. haemolyticus и C. albicans определен для 0,1 % хлоргексидина биглюконата.</p></abstract><trans-abstract xml:lang="en"><p>Background. Caries in children undergoing the orthodontic treatment is caused by the complex of adverse factors the most important of which is the microflora of the tooth plaque. Methods. 47 patients of 9-15 years with дистальной окклюзией during the orthodontic treatment in different follow-up period are examined: in 1, 6 and 18 months. Authors studied features of qualitative and quantitative structure of the microbiocenosis of the tooth plaque and estimated the level of sensitivity of microbiota representatives to antiseptics. Results. From the tooth plaque biomaterial in 25 % of cases allocated mycosis of the type Candida albicans together with the high level of microorganisms of the caries-inducing and associative groups (Streptococcus, Enterococcus, Staphylococcus, Neisseria, Micrococcus, Corynebacterium, Klebsiella). The majority of strains have shown the expressed resistance to 0.01 % miramistin. The highest level of the minimum overwhelming concentration in relation to the cultures of S. aureus, S. epidermidis, S. haemolyticus and C. albicans was defined for 0.1 % chlorine hexidine bigluconate. Conclusions. The obtained data allowed showing that orthodontic treatment of children by fixed equipment promotes constant increase in the level of the tooth plaque microbiota and is the important risk factor of caries. Representatives of the microbiota during the treatment can adapt for the specific conditions of existence and increase resistance to some kinds of the antiseptic agents.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>микробиоценоз</kwd><kwd>хлоргексидин</kwd><kwd>мирамистин</kwd><kwd>индекс активности антисептика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>microbiocenosis</kwd><kwd>chlorine hexidine</kwd><kwd>miramistin</kwd><kwd>the index of antiseptics activity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гудкова Е.И., Красильников А.П., Адарченко, А.А. Методы испытания противомикробной активности антисептиков профилактического назначения: методические указания № 11-13-197, утв. МЗРБ 16.01.1997 г. Минск, 1997. 27 с.</mixed-citation><mixed-citation xml:lang="en">Гудкова Е.И., Красильников А.П., Адарченко, А.А. 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