<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-717</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>КЛИНИКО-ФУНКЦИОНАЛЬНАЯ ХАРАКТЕРИСТИКА ОРГАНОВ РЕЧИ И СЛУХА У ПАЦИЕНТОВ СО СТАБИЛЬНЫМ ТЕЧЕНИЕМ ХРОНИЧЕСКОЙ ОБСТРУКТИВНОЙ БОЛЕЗНИ ЛЕГКИХ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL AND FUNCTIONAL CHARACTERISTICS OF THE SPEECH AND HEARING ORGANS OF THE PATIENTS HAVING THE STABLE CHRONIC OBSTRUCTIVE PULMONARY DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гилифанов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gilifanov</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">gilifanov@pochta.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Невзорова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nevzorova</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артюшкин</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Artyushkin</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлуш</surname><given-names>Д. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlush</surname><given-names>D. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.I. Mechnikov North-West State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2014</year></pub-date><volume>0</volume><issue>1</issue><fpage>45</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гилифанов Е.А., Невзорова В.А., Артюшкин С.А., Павлуш Д.Г., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Гилифанов Е.А., Невзорова В.А., Артюшкин С.А., Павлуш Д.Г.</copyright-holder><copyright-holder xml:lang="en">Gilifanov E.A., Nevzorova V.A., Artyushkin S.A., Pavlush D.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/717">https://www.tmj-vgmu.ru/jour/article/view/717</self-uri><abstract><p>Рассматриваются особенности функционального состояния гортани и уха у 49 пациентов с хронической обструктивной болезнью легких II-III стадии в период стабилизации. Наиболее значимые изменения выявлены в гортани: хронический катаральный ларингит (23 наблюдения), хронический гиперпластический ларингит (6 наблюдений) и отеком Рейнке (6 наблюдений). Существенных нарушений функции органа слуха не обнаружено.</p></abstract><trans-abstract xml:lang="en"><p>The affection of the upper respiratory tract (ear, nose, throat - ENT) is the earliest and most frequent secondary diseases of the obstructive lung disease known as chronic obstructive pulmonary disease (COPD), chronic obstructive lung disease or chronic obstructive airway disease. The above-mentioned combination of the diseases significantly reduces the patients' life quality, results in COPD exacerbation making it necessary to reconsider the treatment program. Methods. The examination of 49 smoking patients aged 51-65 having the stable clinical course of COPD from 2 to 3 grades. The control group was formed of 50 nonsmoking healthy volunteers. Studies by means of otomicroscopy, otoendoskopy, audiologic examination and fibro endoscopic evaluation of larynx, stroboscopy. Results. Indicators of aerated blood ventilation in the group under study and C group were within normal limits. COPD led to the most significant changes in the larynx: chronic catarrhal laryngitis (23 cases), chronic hyperplastic laryngitis (6 cases) and Reinke edema (6 cases). Significant dysfunctions of the auditory organs were absent. Conclusions. The damaging effect of tobacco smoke and its components dissolved in saliva stands out against the other reasons of the functional (incl. phonatoric) imparity of larynx in the time of stabilization of COPD. Taking into account the findings we can recommend adding to the Medical Examination Report of COPD patients an otolaryngologist's advice as its medical comment enables to complement the treatment program.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический ларингит</kwd><kwd>отек Рейнке</kwd><kwd>табачный дым</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic laryngitis</kwd><kwd>Reinke edema</kwd><kwd>tobacco smoke</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Авдеев С.Н. Хроническая обструктивная болезнь легких как системное заболевание // Пульмонология. 2007. № 2. С. 104-112.</mixed-citation><mixed-citation xml:lang="en">Авдеев С.Н. Хроническая обструктивная болезнь легких как системное заболевание // Пульмонология. 2007. № 2. С. 104-112.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гланц С. Медико-биологическая статистика. М.: Практика, 1999. 459 с.</mixed-citation><mixed-citation xml:lang="en">Гланц С. Медико-биологическая статистика. М.: Практика, 1999. 459 с.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Невзорова В.А., Гилифанов Е.А., Тилик Т.В. Клинические проявления патологии дыхательных путей при хронической обструктивной болезни легких // Рос. оторинолар. 2010. № 6. С. 83-86.</mixed-citation><mixed-citation xml:lang="en">Невзорова В.А., Гилифанов Е.А., Тилик Т.В. Клинические проявления патологии дыхательных путей при хронической обструктивной болезни легких // Рос. оторинолар. 2010. № 6. С. 83-86.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Рябова М.Е., Немых О.В. Хронический ларингит. Принципы патогенетического лечения. СПб.: Диалог, 2010. 140 с.</mixed-citation><mixed-citation xml:lang="en">Рябова М.Е., Немых О.В. Хронический ларингит. Принципы патогенетического лечения. СПб.: Диалог, 2010. 140 с.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. Болезни органов дыхания и табакокурение // Тер. архив. 2009. № 3. С. 5-9.</mixed-citation><mixed-citation xml:lang="en">Чучалин А.Г. Болезни органов дыхания и табакокурение // Тер. архив. 2009. № 3. С. 5-9.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г., Синопальников А.И., Козлов РС. [и др.]. Внебольничная пневмония у взрослых // Клин. микробиол. антимикроб. химиотер. 2010. Т. 12, № 3. С. 186-225.</mixed-citation><mixed-citation xml:lang="en">Чучалин А.Г., Синопальников А.И., Козлов РС. [и др.]. Внебольничная пневмония у взрослых // Клин. микробиол. антимикроб. химиотер. 2010. Т. 12, № 3. С. 186-225.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Шульцев Г.П., Висин А.Н. Системные эффекты курения // Клин. медицина. 1992. № 2. С. 17-22.</mixed-citation><mixed-citation xml:lang="en">Шульцев Г.П., Висин А.Н. Системные эффекты курения // Клин. медицина. 1992. № 2. С. 17-22.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Braunstahl G.J. United airways concept: what does it teach us about systemic inflammation in airways disease? // Proc. Am. Thorac. Soc. 2009. Vol. 6, No. 8. Р. 652-654.</mixed-citation><mixed-citation xml:lang="en">Braunstahl G.J. United airways concept: what does it teach us about systemic inflammation in airways disease? // Proc. Am. Thorac. Soc. 2009. Vol. 6, No. 8. Р. 652-654.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Cvejic L., Harding R., Churchward T. [et al.]. Laryngeal penetration and aspiration in individuals with stable COPD // Respirology. 2011. Vol. 16, No. 2. Р. 269-275.</mixed-citation><mixed-citation xml:lang="en">Cvejic L., Harding R., Churchward T. [et al.]. Laryngeal penetration and aspiration in individuals with stable COPD // Respirology. 2011. Vol. 16, No. 2. Р. 269-275.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Effat K.G. Otoscopic appearances and tympanometric changes in Narghilesmokers // J. Laryngol. Otol. 2004. Vol. 118, No. 10. Р. 818-821.</mixed-citation><mixed-citation xml:lang="en">Effat K.G. Otoscopic appearances and tympanometric changes in Narghilesmokers // J. Laryngol. Otol. 2004. Vol. 118, No. 10. Р. 818-821.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Molimard M., Le Gros V., Robinson P. [et al.]. Prevalence and associated factors of oropharyngeal side effects inusersof inhaled corticosteroids in a real-life setting // J. Aerosol. Med. Pulm. Drug. Deliv. 2010. Vol. 23, No. 2. Р. 91-95.</mixed-citation><mixed-citation xml:lang="en">Molimard M., Le Gros V., Robinson P. [et al.]. Prevalence and associated factors of oropharyngeal side effects inusersof inhaled corticosteroids in a real-life setting // J. Aerosol. Med. Pulm. Drug. Deliv. 2010. Vol. 23, No. 2. Р. 91-95.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Nondahl D.M., Cruickshanks K.J., Dalton D.S. [et al.]. Serum cotinine level and incident hearing loss: a case-control study // Arch. Otolaryngol. Head Neck Surg. 2004. Vol. 130, No. 11. Р. 1260-1264.</mixed-citation><mixed-citation xml:lang="en">Nondahl D.M., Cruickshanks K.J., Dalton D.S. [et al.]. Serum cotinine level and incident hearing loss: a case-control study // Arch. Otolaryngol. Head Neck Surg. 2004. Vol. 130, No. 11. Р. 1260-1264.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Oliveira M.F., Rodrigues M.K., Treptow E. [et al.]. Effects of oxygen supplementation on cerebral oxygenation duringexercise inchronic obstructive pulmonary disease patients notentitledto long-term oxygentherapy // Clin. Physiol. Funct. Imaging. 2012. Vol. 32, No.1. Р. 52-58.</mixed-citation><mixed-citation xml:lang="en">Oliveira M.F., Rodrigues M.K., Treptow E. [et al.]. Effects of oxygen supplementation on cerebral oxygenation duringexercise inchronic obstructive pulmonary disease patients notentitledto long-term oxygentherapy // Clin. Physiol. Funct. Imaging. 2012. Vol. 32, No.1. Р. 52-58.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Sakae F.A., Imamura R., Sennes L.U. [et al.]. Elastic fibers in Reinke’s edema // Ann. Otol. Rhinol. Laryngol. 2010. Vol. 119, No. 9. Р. 609-614.</mixed-citation><mixed-citation xml:lang="en">Sakae F.A., Imamura R., Sennes L.U. [et al.]. Elastic fibers in Reinke’s edema // Ann. Otol. Rhinol. Laryngol. 2010. Vol. 119, No. 9. Р. 609-614.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Scott A.S., Baltzman M.A., Chan R. [et al.]. Oxygen desaturation during a 6 min walk test is a sign of nocturnalhypoxemia // Can. Respir. J. 2011. Vol. 18, No. 6. Р. 333-337.</mixed-citation><mixed-citation xml:lang="en">Scott A.S., Baltzman M.A., Chan R. [et al.]. Oxygen desaturation during a 6 min walk test is a sign of nocturnalhypoxemia // Can. Respir. J. 2011. Vol. 18, No. 6. Р. 333-337.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
