pmjТихоокеанский медицинский журналPacific Medical Journal1609-1175TGMUpmj-724Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL RESEARCHESФЕНОМЕН МИКРОКРИСТАЛЛИЧЕСКОГО СТРЕССА ПРИ ОСТЕОАРТРОЗЕOSTEOARTHRITIS AND MICROCRYSTALLINE STRESS PHENOMENONКабалыкМ. А.KabalykM. A.maxi_maxim@mail.ruДубиковА. И.DubikovA. I.noemail@neicon.ruПетрикееваТ. Ю.PetrikeevaT. Y.noemail@neicon.ruКарабцовА. А.KarabtsovA. A.noemail@neicon.ruКузьминИ. И.KuzminI. I.noemail@neicon.ruЧереповскийА. В.CherepovskiyA. V.noemail@neicon.ruТихоокеанский государственный медицинский университетРоссияPacific State Medical UniversityRussian FederationДальневосточный геологический институт ДВО РАНРоссияFar East Geological Institute of the Russian Academy of Sciences Far East BranchRussian Federation201428032014017074Copyright © Кабалык М.А., Дубиков А.И., Петрикеева Т.Ю., Карабцов А.А., Кузьмин И.И., Череповский А.В., 20142014Кабалык М.А., Дубиков А.И., Петрикеева Т.Ю., Карабцов А.А., Кузьмин И.И., Череповский А.В.Kabalyk M.A., Dubikov A.I., Petrikeeva T.Y., Karabtsov A.A., Kuzmin I.I., Cherepovskiy A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tmj-vgmu.ru/jour/article/view/724

Обследованы 110 человек, оперированных по поводу коксартроза II-IV стадии по Каллегрену, и 50 человек, подвергшихся тотальному эндопротезированию тазобедренных суставов после переломов (контроль). Срезы суставного хряща исследовали с помощью методов рентгенструктурного анализа. Минерализация хряща при остеоартрозе зарегистрирована в 72,7 %, в контроле - в 16 % случаев. Распространенность микрокристаллизации увеличивалась по мере прогрессирования рентгенологических симптомов заболевания. Несмотря на большую склонность женщин к ОА минерализация хряща регистрировалась с одинаковой частотой у лиц обоих полов.

The importance of the phenomenon of mineralization of cartilage due to osteoarthritis (OA) proved by an evidence of factors contributing to this process. The object of this study is to determine the clinical and pathogenetic significance of microcrystallisation of the articular cartilage caused by OA. Methods. The study embraced 110 persons operated on coxarthrosis from II to IV grades by (osteoarthritis grading system of) Kellgren and Lawrence and 50 persons undergone hip replacement after a coxal fracture. Methods of X-ray structure analysis used for examining tangential sections of a resected capitular of the femoral bone cartilage. Results. A phenomenon of mineralization of cartilage due to OA amounts 72.7 % of records, in C group - 16 %. The prevalence of microcrystallisation increased in accordance with the progression of radiographic symptoms of disease. Despite women have the greater predisposition to OA, mineralization of cartilage has an even frequency for both sexes. Conclusions. High prevalence of mineralization of articular cartilage due to OA compared with a comparable C group enables to consider the microcrystalline deposition to be an important attendant factor of the pathogenesis of this disease.

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The authors declare that there are no conflicts of interest present.