<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/PmJ1609-1175.2016.4.11-13</article-id><article-id custom-type="elpub" pub-id-type="custom">pmj-77</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Хирургическое лечение рака молочной железы: история и современные тренды</article-title><trans-title-group xml:lang="en"><trans-title>Surgical treatment of a breast cancer: history and trends</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Невожай</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Nevozhay</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Апанасевич</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Apanasevich</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">oncolog222@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет; Краевой клинический центр специализированных видов медицинской помощи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University; Regional Clinical Center of Specialized Medical Care</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2016</year></pub-date><volume>61</volume><issue>4</issue><fpage>11</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Невожай В.И., Апанасевич В.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Невожай В.И., Апанасевич В.И.</copyright-holder><copyright-holder xml:lang="en">Nevozhay V.I., Apanasevich V.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/77">https://www.tmj-vgmu.ru/jour/article/view/77</self-uri><abstract><p>За прошедший век в лечении рака молочной железы (РМЖ) произошло изменение парадигмы хирургической тактики от мастэктомиии (удаления железы с лимфатическими узлами) до лампэктомии (удаления участка железы с опухолью) в сочетании с биопсией сигнального узла, лучевой терапией или онкопластическим вмешательством. В последние годы стратегия хирургического лечения РМЖ пересматривается в сторону эстетической хирургии. Это стало возможно благодаря развитию теоретических представлений о характере заболевания, совершенствованию методов адъювантного лечения. В настоящее время помимо лечебных задач большое значение приобретают достижение оптимального эстетического результата и максимальное продление качественной и социально-активной жизни больных.</p></abstract><trans-abstract xml:lang="en"><p>The research is a literature review dedicated to the evolution of surgical treatment of breast cancer. Over the last century there was a paradigm shift from surgical tactics mastectomy (removal of the aden with the lymph nodes) to a lumpectomy (removal of the tumor from the aden) in combination with a biopsy of the signal node, radiation therapy, or oncoplastic surgery. In recent years, surgical treatment strategy for breast cancer is reviewed in the direction of aesthetic surgery. It has become possible due to the development of theoretical ideas about the nature of the disease, and the improvement of adjuvant therapies. Currently, in addition to medical problems it becomes important an achievement of the optimal aesthetic result and the maximum extension of high-quality and socially active life of patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>радикальная мастэктомия</kwd><kwd>квадрантэктомия</kwd><kwd>лампэктомия</kwd><kwd>эстетический результат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>radical mastectomy</kwd><kwd>quadrantectomy</kwd><kwd>lumpectomy</kwd><kwd>aesthetic result</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2014 году (заболеваемость и смертность) / под ред. А.Д. Каприна [и др.]. М.: МНИОИ им. П.А. Герцена. 2015. 250 с.</mixed-citation><mixed-citation xml:lang="en">Злокачественные новообразования в России в 2014 году (заболеваемость и смертность) / под ред. А.Д. Каприна [и др.]. М.: МНИОИ им. П.А. Герцена. 2015. 250 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Летягин В.П. Эволюция хрургического лечения рака молочной железы // Опухоли женской репродуктивной системы. 2012. № 1. С. 32-36.</mixed-citation><mixed-citation xml:lang="en">Летягин В.П. Эволюция хрургического лечения рака молочной железы // Опухоли женской репродуктивной системы. 2012. № 1. С. 32-36.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Портной С.М., Лактионов К.П. Лечение первично операбельного рака молочной железы // Рак молочной железы / под. ред. Н.Е. Кушлинского [и др.]. М.: РАМН, 2005. С. 267-285.</mixed-citation><mixed-citation xml:lang="en">Портной С.М., Лактионов К.П. Лечение первично операбельного рака молочной железы // Рак молочной железы / под. ред. Н.Е. Кушлинского [и др.]. М.: РАМН, 2005. С. 267-285.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Холдин С.А., Дымарский Л.Ю. Расширенные радикальные операции на молочной железе. Л.: Медицина, 1975. 232 с.</mixed-citation><mixed-citation xml:lang="en">Холдин С.А., Дымарский Л.Ю. Расширенные радикальные операции на молочной железе. Л.: Медицина, 1975. 232 с.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Auchincloss H. Significanse oflocalization and number of axillary metastases in carcinoma of the breast: a justification for a comprehensive operation // Ann. Surg. 1963. Vol. 158, No. 1. P. 37-46.</mixed-citation><mixed-citation xml:lang="en">Auchincloss H. Significanse oflocalization and number of axillary metastases in carcinoma of the breast: a justification for a comprehensive operation // Ann. Surg. 1963. Vol. 158, No. 1. P. 37-46.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Calle R., Pilleron J.P., Schlienger P., Vilcoq J.R. Conservative management of operable breast cancer. Ten years experience at the Foundation Curie // Cancer. 1978. Vol. 42, No. 4. P. 2045-2053.</mixed-citation><mixed-citation xml:lang="en">Calle R., Pilleron J.P., Schlienger P., Vilcoq J.R. Conservative management of operable breast cancer. Ten years experience at the Foundation Curie // Cancer. 1978. Vol. 42, No. 4. P. 2045-2053.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Chan S.W., Cheung P.S., Lam S.H. Cosmetic outcome and percentage of breast volume excision in oncoplastic breast conserving surgery // World J. Surg. 2010. Vol. 34, No. 7. P. 1447-1452.</mixed-citation><mixed-citation xml:lang="en">Chan S.W., Cheung P.S., Lam S.H. Cosmetic outcome and percentage of breast volume excision in oncoplastic breast conserving surgery // World J. Surg. 2010. Vol. 34, No. 7. P. 1447-1452.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Early Breast Cancer Trialists&gt; Collaborative Group. Effects of radiotherapy and surgery in early breast cancer. An overview of the randomized trials // N. Engl. J. Med. 1995. Vol. 333, No. 22. P. 1444-1455.</mixed-citation><mixed-citation xml:lang="en">Early Breast Cancer Trialists&gt; Collaborative Group. Effects of radiotherapy and surgery in early breast cancer. An overview of the randomized trials // N. Engl. J. Med. 1995. Vol. 333, No. 22. P. 1444-1455.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fisher B., Dignam J., Wolmark N. [et al.]. Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17 // J. Clin. Oncol. 1998. Vol. 16, No. 2. P. 441-452.</mixed-citation><mixed-citation xml:lang="en">Fisher B., Dignam J., Wolmark N. [et al.]. Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17 // J. Clin. Oncol. 1998. Vol. 16, No. 2. P. 441-452.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Fisher B., Fisher E.R. Transmigration of lymph node by tumor cells // Science. 1966. Vol. 152, No. 727. P. 1397-1398.</mixed-citation><mixed-citation xml:lang="en">Fisher B., Fisher E.R. Transmigration of lymph node by tumor cells // Science. 1966. Vol. 152, No. 727. P. 1397-1398.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Gilbert H.F. History of irradiation in the primary management of apparently regionally confined breast cancer // Breast: comprehensive management of benign and malignant diseases / ed. by K.I. Bland, E.M. Copeland III. Published by Saunders, 1991. P. 707-713.</mixed-citation><mixed-citation xml:lang="en">Gilbert H.F. History of irradiation in the primary management of apparently regionally confined breast cancer // Breast: comprehensive management of benign and malignant diseases / ed. by K.I. Bland, E.M. Copeland III. Published by Saunders, 1991. P. 707-713.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Giuliano A.E., Kirgan D.M., Guenther J.M., Morton D.L. Lymphatic mapping and sentinel lymphadenectomy for breast cancer // Ann. Surg. 1994. Vol. 220, No. 3. P. 391-401.</mixed-citation><mixed-citation xml:lang="en">Giuliano A.E., Kirgan D.M., Guenther J.M., Morton D.L. Lymphatic mapping and sentinel lymphadenectomy for breast cancer // Ann. Surg. 1994. Vol. 220, No. 3. P. 391-401.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Haagensen C.D. Diseases ofthe breast, 2nd ed. Philadelphia: W.B. Saunders Co., 1971. 1050 p.</mixed-citation><mixed-citation xml:lang="en">Haagensen C.D. Diseases ofthe breast, 2nd ed. Philadelphia: W.B. Saunders Co., 1971. 1050 p.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Haagensen C.D., Stout A.P. Carcinoma of the breast. II. Criteria of operability // Ann. Surg. 1943. Vol. 118, No. 6. Р. 859-870.</mixed-citation><mixed-citation xml:lang="en">Haagensen C.D., Stout A.P. Carcinoma of the breast. II. Criteria of operability // Ann. Surg. 1943. Vol. 118, No. 6. Р. 859-870.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Halsted W.S. The results of operations for the cure of cancer of the breast performed at the Johns Hopkins Hospital from June 1889 to January 1894 // Ann. Surg. 1894. Vol. 20, No. 5. P. 497-555.</mixed-citation><mixed-citation xml:lang="en">Halsted W.S. The results of operations for the cure of cancer of the breast performed at the Johns Hopkins Hospital from June 1889 to January 1894 // Ann. Surg. 1894. Vol. 20, No. 5. P. 497-555.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Inglebi H., Gershon C.J. Comparative anatomy, pathology, and roentgenology of the breast. Philadelphia: University of Pennsylvania Press, 1960. 472 p.</mixed-citation><mixed-citation xml:lang="en">Inglebi H., Gershon C.J. Comparative anatomy, pathology, and roentgenology of the breast. Philadelphia: University of Pennsylvania Press, 1960. 472 p.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Keynes G. The radium treatment of carcinoma of the breast // Br. J. Surg. 1932. Vol. 19, No. 2. P. 415-480.</mixed-citation><mixed-citation xml:lang="en">Keynes G. The radium treatment of carcinoma of the breast // Br. J. Surg. 1932. Vol. 19, No. 2. P. 415-480.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Losken A., Pinell-White X., Hart A.M. [et al.]. The oncoplastic reduction approach to breast conservation therapy: benefits for margin control // Aesthet. Surg. J. 2014. Vol. 34, No. 8. P. 1185-1191.</mixed-citation><mixed-citation xml:lang="en">Losken A., Pinell-White X., Hart A.M. [et al.]. The oncoplastic reduction approach to breast conservation therapy: benefits for margin control // Aesthet. Surg. J. 2014. Vol. 34, No. 8. P. 1185-1191.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Madden J.L. Modified radical mastectomy // Surg. Gynecol. Obstet. 1965. Vol. 121, No. 6. P. 1221-1230.</mixed-citation><mixed-citation xml:lang="en">Madden J.L. Modified radical mastectomy // Surg. Gynecol. Obstet. 1965. Vol. 121, No. 6. P. 1221-1230.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Meyer W. An improved method of the radical operations for carcinoma of the breast // Med. Rec. 1894. No. 46. P. 746-749.</mixed-citation><mixed-citation xml:lang="en">Meyer W. An improved method of the radical operations for carcinoma of the breast // Med. Rec. 1894. No. 46. P. 746-749.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Murawa P., Murawa D., Adamczyk B. [et al.]. Breast cancer: actual methods of treatment and future trends // Rep. Pract. Oncol. Radiother. 2014. Vol. 19, No. 3. P. 165-172.</mixed-citation><mixed-citation xml:lang="en">Murawa P., Murawa D., Adamczyk B. [et al.]. Breast cancer: actual methods of treatment and future trends // Rep. Pract. Oncol. Radiother. 2014. Vol. 19, No. 3. P. 165-172.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Patey D.H., Dyson WH. The prognosis of carcinoma of the breast in relation to the type of operation performed // Br. J. Cancer. 1948. Vol. 1, No. 2 P. 7-13.</mixed-citation><mixed-citation xml:lang="en">Patey D.H., Dyson WH. The prognosis of carcinoma of the breast in relation to the type of operation performed // Br. J. Cancer. 1948. Vol. 1, No. 2 P. 7-13.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Toth B.A., Lappert P. Modified skin incisions for mastectomy: the need for plastic surgical input in preoperative planning // Plast. Reconstr. Surg. 1991. Vol. 87, No. 6. P. 1048-1053.</mixed-citation><mixed-citation xml:lang="en">Toth B.A., Lappert P. Modified skin incisions for mastectomy: the need for plastic surgical input in preoperative planning // Plast. Reconstr. Surg. 1991. Vol. 87, No. 6. P. 1048-1053.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Urban J.A. Radical mastectomy in continuity with en bloc resection of internal mammary lymph-node chain // Cancer. 1952. No. 5. P. 992-1008.</mixed-citation><mixed-citation xml:lang="en">Urban J.A. Radical mastectomy in continuity with en bloc resection of internal mammary lymph-node chain // Cancer. 1952. No. 5. P. 992-1008.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Veiga D.F., Veiga-Filho J., Ribeiro L.M. [et al.]. Evaluations of aesthetic outcomes of oncoplastic surgery by surgeons of different gender and specialty: a prospective controlled study // Breast. 2011. Vol. 20, No. 5. P. 407-412.</mixed-citation><mixed-citation xml:lang="en">Veiga D.F., Veiga-Filho J., Ribeiro L.M. [et al.]. Evaluations of aesthetic outcomes of oncoplastic surgery by surgeons of different gender and specialty: a prospective controlled study // Breast. 2011. Vol. 20, No. 5. P. 407-412.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Veronesi U., Banfi A., Salvadori B. Breast conservation is the treatment of choice in small breast cancer: long-term results of a randomized trial // Eur. J. Cancer. 1990. Vol. 26, No. 6. P. 668-670.</mixed-citation><mixed-citation xml:lang="en">Veronesi U., Banfi A., Salvadori B. Breast conservation is the treatment of choice in small breast cancer: long-term results of a randomized trial // Eur. J. Cancer. 1990. Vol. 26, No. 6. P. 668-670.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Veronesi U., Volterrani F., Luini A. [et al.]. Quadrantectomy versus lumpectomy for small size breast cancer // Eur. J.Cancer. 1990. Vol. 26, No. 6. P. 671-673.</mixed-citation><mixed-citation xml:lang="en">Veronesi U., Volterrani F., Luini A. [et al.]. Quadrantectomy versus lumpectomy for small size breast cancer // Eur. J.Cancer. 1990. Vol. 26, No. 6. P. 671-673.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">World Cancer Report 2014. URL: http://www.esmo.org/On-cology-News/World-Cancer-Report-2014 (дата обращения: 14.06.2016).</mixed-citation><mixed-citation xml:lang="en">World Cancer Report 2014. URL: http://www.esmo.org/On-cology-News/World-Cancer-Report-2014 (дата обращения: 14.06.2016).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
