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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmj</journal-id><journal-title-group><journal-title xml:lang="ru">Тихоокеанский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Pacific Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-1175</issn><publisher><publisher-name>TGMU</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pmj-808</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Действие экстрактов Reynoutria japonica в условиях различной стрессогенности</article-title><trans-title-group xml:lang="en"><trans-title>EFFECTS OF EXTRACTS OF REYNOUTRIAfAPONICA UNDER STRESS-INDUCING FACTORs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якименко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakimenko</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">lyudmila.yakimenko@vvsu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зорикова</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Zorikova</surname><given-names>S. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зорикова</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zorikova</surname><given-names>O. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маняхин</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Manyakhin</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Межведомственный научно-образовательный центр «Растительные ресурсы» (Горнотаежная станция им. В.Л. Комарова ДВО РАН Владивостокский государственный университет экономики и сервиса)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Interdepartmental Research and Educational Centre “Plant Resources” (The V. L. Komarov Mountain-Taiga Station, FEB RAS -Vladivostok State University of Economics and Service)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Горнотаежная станция им. В.Л. Комарова Дальневосточного отделения Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The V. L. Komarov Mountain-Taiga Station, FEB RAS</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2013</year></pub-date><volume>0</volume><issue>2</issue><fpage>38</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Якименко Л.В., Зорикова С.П., Зорикова О.Г., Маняхин А.Ю., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Якименко Л.В., Зорикова С.П., Зорикова О.Г., Маняхин А.Ю.</copyright-holder><copyright-holder xml:lang="en">Yakimenko L.V., Zorikova S.P., Zorikova O.G., Manyakhin A.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tmj-vgmu.ru/jour/article/view/808">https://www.tmj-vgmu.ru/jour/article/view/808</self-uri><abstract><p>Изучали действие сухого и водного экстрактов Reynoutria japonica на центральную нервную систему лабораторных животных. Проведенные эксперименты показали, что препараты R. japonica проявляют биологическую активность адаптогенного и анксиолитического характера, смещая соотношение пассивно-оборонительных и исследовательских компонентов поведения в сторону последних при тестировании в открытом поле и преодолевая тревожно-фобические проявления в приподнятом крестообразном лабиринте в условиях максимальной сенсорной нагрузки.</p></abstract><trans-abstract xml:lang="en"><p>The authors have studied effects of dry and water-based extracts of Reynoutria japonica on the central nervous system of laboratory animals. As reported, R. japonica-based medications exhibit biological activity of adaptogene and anxiolytic nature, thus shifting the ratio of passive defensive and investigative components of behaviour to the latter ones during in-field testing and surmounting anxiophobic manifestations in the elevated plus maze in case of the maximum sensory load.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рейнутрия японская</kwd><kwd>экстракты</kwd><kwd>нейротропная активность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Reynoutriajaponica</kwd><kwd>extracts</kwd><kwd>neurotropic activity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Зорикова С.П., Зорикова О.Г. Интродукция рейнутрии японской (Reynoutria japonica Houtt.) в условиях юга Приморского края // Биологические исследования на ГТС: сб. научных трудов. 2011. № 12. 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