pmjТихоокеанский медицинский журналPacific Medical Journal1609-1175TGMUpmj-913Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL RESEARCHESОценка современных методов общей анестезии с позиций обеспечения нейропротекторного эффекта в реконструктивной хирургии брахиоцефальных артерийEstimating the present-day methods of general anaesthesia as those ensuring neuroprotective effect in the reconstructive surgery of brachiocephalic arteriesШмелевВ. В.ShmelevV. V.vsh270104@mail.ruНеймаркМ. И.NeimarkM. I.noemail@neicon.ruАлтайский государственный медицинский университетРоссияAltai State Medical UniversityRussian Federation201228092012036266Copyright © Шмелев В.В., Неймарк М.И., 20122012Шмелев В.В., Неймарк М.И.Shmelev V.V., Neimark M.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tmj-vgmu.ru/jour/article/view/913

У 130 пациентов 45-68 лет проведена оценка эффективности тотальной внутривенной анестезии диприваном и ингаляционной анестезии севофлураном при каротидной эндартерэктомии. Исследовались параметры гемодинамики, мозгового кровообращения, маркеры мозгового повреждения. Показано, что анестезия севофлураном вызывает меньшую депрессию гемодинамики, поддерживает более оптимальный уровень мозгового кровотока, что лимитирует ишемическое и реперфузионное повреждение головного мозга и сопровождается меньшим числом послеоперационных осложнений.

The authors have estimated the efficiency of the total intravenous anaesthesia with Diprivan and inhalation anaesthesia with Sevoflurane in case of carotid endarterectomy in 130 patients aged 45 to 68 years old. Investigating indices of the hemodynamics, cerebral circulation and markers of brain injury allowed to conclude that the anaesthesia with Sevoflurane has caused lesser depression of the hemodynamics, maintained more optimal level of the cerebral blood flow that limited the ischemic and reperfusion brain injuries followed by the lesser number of the post-operative complications.

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The authors declare that there are no conflicts of interest present.