pmjТихоокеанский медицинский журналPacific Medical Journal1609-1175TGMUpmj-930Research ArticleОБЗОРЫREVIEWSЭндотелиальный (интимальный) механизм регуляции мозговой гемодинамики: трансформация взглядовENDOTHELIAL (INTIMAL) MECHANISM OF CEREBRAL HEMODYNAMICS REGULATION: CHANGING VIEWSЧертокВ. М.ChertokV. M.chertokv@mail.ruКоцюбаА. Е.KotsyubaA. E.noemail@neicon.ruВладивостокский государственный медицинский университетРоссияVladivostok State Medical UniversityRussian Federation201228062012021726Copyright © Черток В.М., Коцюба А.Е., 20122012Черток В.М., Коцюба А.Е.Chertok V.M., Kotsyuba A.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tmj-vgmu.ru/jour/article/view/930

В обзоре рассмотрены существующие представления о роли эндотелия сосудов в регуляции мозговой гемодинамики - от полного отрицания такой возможности до признания за эндотелиальным механизмом ведущей роли в управлении функциями сосудов. Обобщены результаты собственных исследований, а также данные литературы за последние полвека по эндотелиальному (интимальному) механизму регуляции кровотока. По мнению авторов, адекватное кровоснабжение головного мозга представляет собой результат взаимодействия нескольких механизмов, изучение которых позволит установить истинное значение эндотелия в единой системе управления мозговым кровообращением.

The literature overview describes modern standpoints about the role of vessel endothelium in regulating cerebral hemodynamics - from complete denial of this possibility to recognition of the leading role of endothelial mechanism in controlling vessel functions. The paper summarises results of authors’ researches and literature over the last fifty years into the endothelial (intimal) mechanism of blood circulation regulation. As reported, the adequate blood supply of brain results from interaction between several mechanisms. Researching these mechanisms will allow identify the role of endothelium in the single system of blood supply of brain.

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