On pathogenicity of opportunistic pathogens
Abstract
This lecture discusses mechanisms of activation of
disease-causing properties in the opportunistic microorganisms.
The author's studies indicate that the signs of pathogenicity of actinomycetes
known to inhabit the oral cavity appear at the early
development stage of microbial population. As supposed, the microorganisms
known to inhabit mucous tunic and skin are characterized
by full life cycle, and therefore are host-avirulent. Exposed
to the environment, there is evident accumulation of microorganisms
with incomplete life cycle capable of activating pathogenic
potential. In author's opinion, transformation in actinomycetes
and other opportunistic microorganisms from resident into
pathogenous state can be caused by changes in regulation of their
life cycle.
disease-causing properties in the opportunistic microorganisms.
The author's studies indicate that the signs of pathogenicity of actinomycetes
known to inhabit the oral cavity appear at the early
development stage of microbial population. As supposed, the microorganisms
known to inhabit mucous tunic and skin are characterized
by full life cycle, and therefore are host-avirulent. Exposed
to the environment, there is evident accumulation of microorganisms
with incomplete life cycle capable of activating pathogenic
potential. In author's opinion, transformation in actinomycetes
and other opportunistic microorganisms from resident into
pathogenous state can be caused by changes in regulation of their
life cycle.
About the Authors
В. Мельников
Международный научно-технический центр
Russian Federation
Russian Federation
V. G. Melnikov
International Science and Technology Centre
Russian Federation
Russian Federation
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Review
For citations:
, Melnikov V.G. On pathogenicity of opportunistic pathogens. Pacific Medical Journal. 2010;(3):15-18. (In Russ.)
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